JOSE VICENTE
CASTELL RIPOLL
EMÉRITO/A UNIVERSIDAD
Maastricht University
Maastricht, HolandaMaastricht University-ko ikertzaileekin lankidetzan egindako argitalpenak (14)
2024
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Cluster-Partial Least Squares (c-PLS) regression analysis: Application to miRNA and metabolomic data
Analytica chimica acta, Vol. 1286, pp. 342052
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Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders
Alternatives to Laboratory Animals, Vol. 52, Núm. 2, pp. 117-131
2022
2021
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A Model-Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs
Clinical Pharmacology and Therapeutics, Vol. 110, Núm. 5, pp. 1293-1301
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Comparing in vitro human liver models to in vivo human liver using RNA-Seq
Archives of Toxicology, Vol. 95, Núm. 2, pp. 573-589
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Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes
Archives of Toxicology, Vol. 95, Núm. 9, pp. 3049-3062
2018
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A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity
Archives of Toxicology
2016
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Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective
Archives of Toxicology, Vol. 90, Núm. 9, pp. 2215-2229
2014
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Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices
Toxicology, Vol. 323, pp. 61-69
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Testing chemical carcinogenicity by using a transcriptomics heparg-based model?
EXCLI Journal, Vol. 13, pp. 623-637
2013
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A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR)
Journal of Proteome Research, Vol. 12, Núm. 6, pp. 2732-2741
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Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models
Carcinogenesis, Vol. 34, Núm. 6, pp. 1393-1402
2011
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Human embryonic stem cell derived hepatocyte-like cells as a tool for In Vitro hazard assessment of chemical carcinogenicity
Toxicological Sciences, Vol. 124, Núm. 2, pp. 278-290
1996
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The Use of Biokinetics and In Vitro Methods in Toxicological Risk Evaluation: The Report and Recommendations of ECVAM Workshop 15
ATLA Alternatives to Laboratory Animals, Vol. 24, Núm. 4, pp. 473-497