Publicaciones en colaboración con investigadores/as de Maastricht University (14)

2024

  1. Cluster-Partial Least Squares (c-PLS) regression analysis: Application to miRNA and metabolomic data

    Analytica chimica acta, Vol. 1286, pp. 342052

  2. Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders

    Alternatives to Laboratory Animals, Vol. 52, Núm. 2, pp. 117-131

2022

  1. Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds

    Scientific Data

2021

  1. A Model-Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs

    Clinical Pharmacology and Therapeutics, Vol. 110, Núm. 5, pp. 1293-1301

  2. Comparing in vitro human liver models to in vivo human liver using RNA-Seq

    Archives of Toxicology, Vol. 95, Núm. 2, pp. 573-589

  3. Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes

    Archives of Toxicology, Vol. 95, Núm. 9, pp. 3049-3062

2018

  1. A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

    Archives of Toxicology

2016

  1. Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective

    Archives of Toxicology, Vol. 90, Núm. 9, pp. 2215-2229

2014

  1. Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices

    Toxicology, Vol. 323, pp. 61-69

  2. Testing chemical carcinogenicity by using a transcriptomics heparg-based model?

    EXCLI Journal, Vol. 13, pp. 623-637

2013

  1. A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR)

    Journal of Proteome Research, Vol. 12, Núm. 6, pp. 2732-2741

  2. Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

    Carcinogenesis, Vol. 34, Núm. 6, pp. 1393-1402

2011

  1. Human embryonic stem cell derived hepatocyte-like cells as a tool for In Vitro hazard assessment of chemical carcinogenicity

    Toxicological Sciences, Vol. 124, Núm. 2, pp. 278-290

1996

  1. The Use of Biokinetics and In Vitro Methods in Toxicological Risk Evaluation: The Report and Recommendations of ECVAM Workshop 15

    ATLA Alternatives to Laboratory Animals, Vol. 24, Núm. 4, pp. 473-497