ResPediaTu

Genetic analysis in solid tumours in children. At European level, we participate in the establishment of a uniform nomenclature, a standard operating procedure and quality validation studies, essential to obtain and maintain a high quality of the results of fluorescent in situ hybridisation, single nucleotide polymorphism and sequencing (FISH, SNPs and NGS) used for therapeutic stratification in neuroblastoma. Identification of new genetic factors and digital microscopic analysis with prognostic value in low prevalence tumours (rare tumours). Obtaining and characterising cell lines derived from fresh tumours of neuroblastic and skeletogenic tumours in children. Establishment and characterisation of in vivo models (2D and 3D) of neuroblastic tumours. Marker expression studies in paediatric solid tumours and colorectal carcinoma. Digital pathology studies of the tumour microenvironment.