COPOS
Research group on cellular and organic Physiopathology of oxidative stress and rare diseases
Date of inception 20 November 2017
Leader: FEDERICO VICENTE PALLARDO CALATAYUD
Department: Physiology
The group focuses its efforts on unravelling the pathophysiological mechanisms of rare diseases, mainly progeroid processes and neuromuscular diseases. This research helps to understand the process of organic ageing. We have provided a new animal model of Charcot-Marie-Tooth disease and contributed to a better understanding of the relationship between oxidative stress and gene regulation mechanisms modulated by epigenetic factors. Down's syndrome, the disease that most frequently develops mental deficiency, has also been approached from the perspective of changes in cell turnover processes, contributing to elucidating its pathophysiology. In Lafora disease, which has a poor prognosis, we have described the presence of oxidative stress and the lack of antioxidant defence.
Researchers
Contributors
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Prevailing specialties (top 3)
Obtained from publications help
Obtained from publications
The displayed thematic specialties have been obtained through the application of artificial intelligence models, derived as a result of the Hercules Project from those publications with an abstract, provided that the record does not come from commercial databases, which impose restrictions on data usage.
The displayed thematic specialties have been obtained through the application of artificial intelligence models, derived as a result of the Hercules Project from those publications with an abstract, provided that the record does not come from commercial databases, which impose restrictions on data usage.
Former members (2)
- IBAÑEZ CABELLOS, JOSE SANTIAGO 20172018
- SECO CERVERA, MARTA Contributor 20172020