Studying the neurogenic potential of local progenitors in the adult olfactory bulb and their biocompatibility with graphene

  1. Defterali, Çagla
unter der Leitung von:
  1. Carlos Vicario Abejón Doktorvater/Doktormutter

Universität der Verteidigung: Universidad Autónoma de Madrid

Fecha de defensa: 03 von Juli von 2015

Gericht:
  1. Paola Bovolenta Nicolao Präsident/in
  2. Enrique de la Rosa Cano Sekretär/in
  3. Carlos Crespo Ruperez Vocal
  4. Soledad Alcántara Vocal
  5. Helena Mira Aparicio Vocal

Art: Dissertation

Teseo: 393168 DIALNET lock_openBiblos-e Archivo editor

Zusammenfassung

Literature suggests that here are NSC and progenitor cells within the adult mouse olfactory bulb (OB). This study looks into the existence of a neurogenic niche within this area of the brain by characterizing the NSC and progenitor cell populations and their differentiation into mature neurons. In addition, carbón-based nanomaterials such as graphene, has been studied as favourable materials for use with the neural tissue. Accordingly, the second main objective of this thesis was to evaluate the biocampatibility potential of graphene with the olfactory bulb tissue in vitro and in vivo.