Studying the neurogenic potential of local progenitors in the adult olfactory bulb and their biocompatibility with graphene

  1. Defterali, Çagla
Dirigida per:
  1. Carlos Vicario Abejón Director/a

Universitat de defensa: Universidad Autónoma de Madrid

Fecha de defensa: 03 de de juliol de 2015

Tribunal:
  1. Paola Bovolenta Nicolao President/a
  2. Enrique de la Rosa Cano Secretari/ària
  3. Carlos Crespo Ruperez Vocal
  4. Soledad Alcántara Vocal
  5. Helena Mira Aparicio Vocal

Tipus: Tesi

Teseo: 393168 DIALNET lock_openBiblos-e Archivo editor

Resum

Literature suggests that here are NSC and progenitor cells within the adult mouse olfactory bulb (OB). This study looks into the existence of a neurogenic niche within this area of the brain by characterizing the NSC and progenitor cell populations and their differentiation into mature neurons. In addition, carbón-based nanomaterials such as graphene, has been studied as favourable materials for use with the neural tissue. Accordingly, the second main objective of this thesis was to evaluate the biocampatibility potential of graphene with the olfactory bulb tissue in vitro and in vivo.