Publicaciones en colaboración con investigadores/as de King Saud University (21)

2024

  1. Activation of p53 signaling and regression of breast and prostate carcinoma cells by spirooxindole-benzimidazole small molecules

    Frontiers in Pharmacology, Vol. 15

  2. Exploring the synthesis and application of a pyrazole derivative in corrosion protection: Theoretical modeling and experimental investigations

    Journal of Molecular Structure, Vol. 1312

  3. Synthesis, X-ray analysis, and antiviral evaluation of allohimachalol: Insights into stereoselectivity in epoxidation

    Journal of Molecular Structure, Vol. 1305

2023

  1. A MEDT study of the mechanism and selectivity of the hetero-Diels–Alder reaction between 3-benzoylpyrrolo[1,2-c][1,4]-benzoxazine-1,2,4-trione and vinyl acetate

    Chemistry of Heterocyclic Compounds, Vol. 59, Núm. 3, pp. 165-170

  2. A novel alpha-amylase inhibitor-based spirooxindole-pyrrolidine-clubbed thiochromene-pyrzaole pharmacophores: Unveiling the [3+2] cycloaddition reaction by molecular electron density theory

    Chemical Biology and Drug Design, Vol. 102, Núm. 5, pp. 972-995

  3. Exploring Regio- and Stereoselectivity in [3+2] Cycloaddition: Molecular Electron Density Theory Approach for Novel Spirooxindole-Based Benzimidazole with Pyridine Spacer

    Crystals, Vol. 13, Núm. 7

  4. Investigation of the molecular mechanism and diastereoselectivity in the [3 + 2] cycloaddition reaction between acetonitrile oxide and Cis-3,4-Dichlorocyclobutene: Insights from MEDT and docking study

    Computational and Theoretical Chemistry, Vol. 1228

  5. New spiro-indeno[1,2-b]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insights

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 38, Núm. 1

  6. Stereoselective Synthesis of a Novel Series of Dispiro-oxindolopyrrolizidines Embodying Thiazolo[3,2-a]benzimidazole Motif: A Molecular Electron Density Theory Study of the Mechanism of the [3 + 2] Cycloaddition Reaction

    Chemistry (Switzerland), Vol. 5, Núm. 4, pp. 2392-2405

  7. Synthesis and Characterization of New Spirooxindoles Including Triazole and Benzimidazole Pharmacophores via [3+2] Cycloaddition Reaction: An MEDT Study of the Mechanism and Selectivity

    Molecules, Vol. 28, Núm. 19

  8. Synthesis and anti-Cancer Activity of a New Hybrid Based Spirooxindole-Pyrrolidine -Thiochromene Scaffolds via [3 + 2] Cycloaddition Reaction: Computational Investigation

    Polycyclic Aromatic Compounds, Vol. 43, Núm. 3, pp. 2302-2320

  9. Synthesis, In Vitro and in Cell Study of a New Spirooxindoles-Based N-Alkylated Maleimides Targeting HER2/3 Signaling Pathway

    Polycyclic Aromatic Compounds, Vol. 43, Núm. 6, pp. 5251-5275

2022

  1. A Molecular Electron Density Theory Study of the [3+2] Cycloaddition Reaction of <i>Pseudo(mono)radical</i> Azomethine Ylides with Phenyl Vinyl Sulphone

    ORGANICS, Vol. 3, Núm. 2, pp. 122-136

  2. A Molecular Electron Density Theory Study of the [3+2] Cycloaddition Reaction of an Azomethine Ylide with an Electrophilic Ethylene Linked to Triazole and Ferrocene Units

    Molecules, Vol. 27, Núm. 19

  3. Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies

    International Journal of Molecular Sciences, Vol. 23, Núm. 19

  4. [3 + 2] Cycloadditions in Asymmetric Synthesis of Spirooxindole Hybrids Linked to Triazole and Ferrocene Units: X-ray Crystal Structure and MEDT Study of the Reaction Mechanism

    Symmetry, Vol. 14, Núm. 10

2021

  1. Design, Synthesis, Chemical and Biochemical Insights Into Novel Hybrid Spirooxindole-Based p53-MDM2 Inhibitors With Potential Bcl2 Signaling Attenuation

    Frontiers in Chemistry, Vol. 9

  2. Straightforward regio- and diastereoselective synthesis, molecular structure, intermolecular interactions and mechanistic study of spirooxindole-engrafted rhodanine analogs

    Molecules, Vol. 26, Núm. 23

  3. Synthesis of Spirooxindole Analogs Tethered Pyrazole Scaffold as Acetylcholinesterase Inhibitors

    ChemistrySelect, Vol. 6, Núm. 48, pp. 14039-14053

2012

  1. Electrochemical monitoring of the oxidative coupling of alkynes catalyzed by triphenylphosphine gold complexes

    Electrochemistry Communications, Vol. 19, Núm. 1, pp. 145-148