ANA
LLUCH HERNANDEZ
EMÉRITO/A UNIVERSIDAD
Fundación Jiménez Díaz
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Fundación Jiménez Díaz (28)
2023
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Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells
Cell Death and Differentiation, Vol. 30, Núm. 5, pp. 1366-1381
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High VEGFR3 Expression Reduces Doxorubicin Efficacy in Triple-Negative Breast Cancer
International journal of molecular sciences, Vol. 24, Núm. 4
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Triple-Negative PAM50 Non-Basal Breast Cancer Subtype Predicts Benefit from Extended Adjuvant Capecitabine
Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 29, Núm. 2, pp. 389-400
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miR-146a-5p Promotes Angiogenesis and Confers Trastuzumab Resistance in HER2+ Breast Cancer
Cancers, Vol. 15, Núm. 7
2022
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Targeting HER2-AXL heterodimerization to overcome resistance to HER2 blockade in breast cancer
Science Advances, Vol. 8, Núm. 20
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mTOR Inhibition and T-DM1 in HER2-Positive Breast Cancer
Molecular Cancer Research, Vol. 20, Núm. 7, pp. 1108-1121
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miR-99a-5p modulates doxorubicin resistance via the COX-2/ABCG2 axis in triple-negative breast cancer: from the discovery to in vivo studies
Cancer Communications
2021
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Preclinical and clinical characterization of fibroblast-derived neuregulin-1 on trastuzumab and pertuzumab activity in HER2-positive breast cancer
Clinical Cancer Research, Vol. 27, Núm. 18, pp. 5096-5108
2020
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Autocrine CCL5 effect mediates trastuzumab resistance by ERK pathway activation in HER2-positive breast cancer
Molecular Cancer Therapeutics, Vol. 19, Núm. 8, pp. 1696-1707
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FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease
Journal of Clinical Investigation, Vol. 130, Núm. 9, pp. 4871-4887
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The hippo pathway transducers yap1/tead induce acquired resistance to trastuzumab in her2-positive breast cancer
Cancers, Vol. 12, Núm. 5
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Tumor-associated fibroblasts promote HER2-targeted therapy resistance through FGFR2 activation
Clinical Cancer Research, Vol. 26, Núm. 6, pp. 1432-1448
2019
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NK cell infiltrates and HLA class I expression in primary HER2 þ breast cancer predict and uncouple pathological response and disease-free survival
Clinical Cancer Research, Vol. 25, Núm. 5, pp. 1535-1545
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Detection of breast cancer stem cell gene mutations in circulating free DNA during the evolution of metastases
Breast Cancer Research and Treatment, Vol. 178, Núm. 2, pp. 251-261
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Dynamic clonal remodelling in breast cancer metastases is associated with subtype conversion
European Journal of Cancer, Vol. 120, pp. 54-64
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High numbers of circulating CD57+ NK cells associate with resistance to her2-specific therapeutic antibodies in HER2+ primary breast cancer
Cancer Immunology Research, Vol. 7, Núm. 8, pp. 1280-1292
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The miRNA-449 family mediates doxorubicin resistance in triple-negative breast cancer by regulating cell cycle factors
Scientific Reports, Vol. 9, Núm. 1
2018
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MSK1 regulates luminal cell differentiation and metastatic dormancy in ER + breast cancer
Nature Cell Biology, Vol. 20, Núm. 2, pp. 211-221
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Erratum to: MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+ breast cancer (Nature Cell Biology, (2018), 20, 2, (211-221), 10.1038/s41556-017-0021-z)
Nature Cell Biology
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Recent insights into the development of preclinical trastuzumab-resistant HER2+ breast cancer models
Current Medicinal Chemistry, Vol. 25, Núm. 17, pp. 1976-1998