JOSE VICENTE
CASTELL RIPOLL
EMÉRITO/A UNIVERSIDAD
Imperial College London
Londres, Reino UnidoPublicaciones en colaboración con investigadores/as de Imperial College London (7)
2022
2018
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A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity
Archives of Toxicology
2013
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A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR)
Journal of Proteome Research, Vol. 12, Núm. 6, pp. 2732-2741
2003
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Comparative studies on the cytochrome P450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems
Drug Metabolism and Disposition, Vol. 31, Núm. 9, pp. 1093-1102
2002
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Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: Molecular mechanisms that determine lower expression in cultured cells
Xenobiotica, Vol. 32, Núm. 6, pp. 505-520
2001
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An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant
Drug Metabolism and Disposition, Vol. 29, Núm. 5, pp. 712-720
1999
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Hepatic metabolism of diclofenac: Role of human CYP in the minor oxidative pathways
Biochemical Pharmacology, Vol. 58, Núm. 5, pp. 787-796