Publications en collaboration avec des chercheurs de Rheinisch-Westfälische Technische Hochschule Aachen University (6)

2022

  1. Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds

    Scientific Data

2021

  1. A Model-Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs

    Clinical Pharmacology and Therapeutics, Vol. 110, Núm. 5, pp. 1293-1301

2019

  1. A physiology-based model of human bile acid metabolism for predicting bile acid tissue levels after drug administration in healthy subjects and bric type 2 patients

    Frontiers in Physiology, Vol. 10, Núm. SEP

2018

  1. A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

    Archives of Toxicology

2017

  1. Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients

    Archives of Toxicology, Vol. 91, Núm. 2, pp. 865-883

2000

  1. Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent

    Hepatology, Vol. 32, Núm. 1, pp. 49-55