JOSE VICENTE
CASTELL RIPOLL
EMÉRITO/A UNIVERSIDAD
MARIA TERESA
DONATO MARTIN
PROF. PERMANENTE LABORAL PPL
Publicacions en què col·labora amb MARIA TERESA DONATO MARTIN (103)
2020
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Improved in vivo efficacy of clinical-grade cryopreserved human hepatocytes in mice with acute liver failure
Cytotherapy, Vol. 22, Núm. 2, pp. 114-121
2019
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Long-term and mechanistic evaluation of drug-induced liver injury in Upcyte human hepatocytes
Archives of Toxicology, Vol. 93, Núm. 2, pp. 519-532
2018
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Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury
Archives of Toxicology, Vol. 92, Núm. 1, pp. 383-399
2016
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A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury
Scientific Reports, Vol. 6
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Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development
Toxicology Letters, Vol. 263, pp. 58-67
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Extending metabolome coverage for untargeted metabolite profiling of adherent cultured hepatic cells
Analytical and Bioanalytical Chemistry, Vol. 408, Núm. 4, pp. 1217-1230
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Human upcyte hepatocytes: Characterization of the hepatic phenotype and evaluation for acute and long-term hepatotoxicity routine testing
Toxicological Sciences, Vol. 152, Núm. 1, pp. 214-229
2015
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High-content screening of drug-induced mitochondrial impairment in hepatic cells: effects of statins
Archives of Toxicology, Vol. 89, Núm. 10, pp. 1847-1860
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Human neonatal hepatocyte transplantation induces long-term rescue of unconjugated hyperbilirubinemia in the Gunn rat
Liver Transplantation, Vol. 21, Núm. 6, pp. 801-811
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LC-MS untargeted metabolomic analysis of drug-induced hepatotoxicity in HepG2 cells
Electrophoresis, Vol. 36, Núm. 18, pp. 2294-2302
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Repression of the nuclear receptor small heterodimer partner by steatotic drugs and in advanced nonalcoholic fatty liver disease
Molecular Pharmacology, Vol. 87, Núm. 4, pp. 582-594
2014
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A simple transcriptomic signature able to predict drug-induced hepatic steatosis
Archives of Toxicology, Vol. 88, Núm. 4, pp. 967-982
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Metabolomics discloses donor liver biomarkers associated with early allograft dysfunction
Journal of Hepatology, Vol. 61, Núm. 3, pp. 564-574
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Neonatal livers: A source for the isolation of good-performing hepatocytes for cell transplantation
Cell Transplantation, Vol. 23, Núm. 10, pp. 1229-1242
2013
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HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: Identification of bioactivable drugs and the potential mechanism of toxicity involved
Archives of Toxicology, Vol. 87, Núm. 6, pp. 1115-1127
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Mangifera indica L. extract and mangiferin modulate cytochrome P450 and UDP-glucuronosyltransferase enzymes in primary cultures of human hepatocytes
Phytotherapy Research, Vol. 27, Núm. 5, pp. 745-752
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Multiparametric evaluation of the cytoprotective effect of the Mangifera indica L. stem bark extract and mangiferin in HepG2 cells
Journal of Pharmacy and Pharmacology, Vol. 65, Núm. 7, pp. 1073-1082
2012
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Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs
Toxicological Sciences, Vol. 127, Núm. 1, pp. 187-198
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Evaluation of cytochrome P450 activities in human hepatocytes in vitro
Methods in Molecular Biology, Vol. 806, pp. 87-97
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High-content imaging technology for the evaluation of drug-induced steatosis using a multiparametric cell-based assay
Journal of Biomolecular Screening, Vol. 17, Núm. 3, pp. 394-400