JOSE VICENTE
CASTELL RIPOLL
EMÉRITO/A UNIVERSIDAD
XAVIER JOSEP
PONSODA I MARTI
CATEDRÁTICO/A DE UNIVERSIDAD
Publicacions en què col·labora amb XAVIER JOSEP PONSODA I MARTI (35)
2004
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Drug metabolism by cultured human hepatocytes: How far are we from the in vivo reality?
ATLA Alternatives to Laboratory Animals, Vol. 32, Núm. 2, pp. 101-110
2003
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Diclofenac induces apoptosis in hepatocytes
Toxicology in Vitro
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Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS
Biochemical Pharmacology, Vol. 66, Núm. 11, pp. 2155-2167
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Human hepatic cell cultures: In vitro and in vivo drug metabolism
ATLA Alternatives to Laboratory Animals
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Induction of hepatic heme oxygenase-1 by diclofenac in rodents: Role of oxidative stress and cytochrome P-450 activity
Journal of Hepatology, Vol. 38, Núm. 6, pp. 776-783
2001
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Drug biotransformation by human hepatocytes. In vitro/in vivo metabolism by cells from the same donor
Journal of Hepatology, Vol. 34, Núm. 1, pp. 19-25
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Expression and induction of a large set of drug-metabolizing enzymes by the highly differentiated human hepatoma cell line BC2
European Journal of Biochemistry, Vol. 268, Núm. 5, pp. 1448-1459
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Role of endogenous nitric oxide in liver-specific functions and survival of cultured rat hepatocytes
Xenobiotica, Vol. 31, Núm. 5, pp. 249-264
2000
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Expression of liver specific-genes in hepatocytes cultured in collagen gel matrix.
Progress in molecular and subcellular biology, Vol. 25, pp. 89-104
1999
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Diclofenac toxicity to hepatocytes: A role for drug metabolism in cell toxicity
Journal of Pharmacology and Experimental Therapeutics, Vol. 288, Núm. 1, pp. 65-72
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Increased toxicity of cocaine on human hepatocytes induced by ethanol: Role of GSH
Biochemical Pharmacology, Vol. 58, Núm. 10, pp. 1579-1585
1998
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Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix
Journal of Cellular Physiology, Vol. 177, Núm. 4, pp. 553-562
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Toxicity and Cell Density Monitoring in Monolayer and Three-dimensional Cultures with the XTT Assay
ATLA Alternatives to Laboratory Animals, Vol. 26, Núm. 3, pp. 331-342
1997
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Evaluation of the Cytotoxic Effects of MEIC Chemicals 31-50 on Primary Culture of Rat Hepatocytes and Hepatic and Non-hepatic Cell Lines
ATLA Alternatives to Laboratory Animals, Vol. 25, Núm. 4, pp. 423-436
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In vitro investigation of the molecular mechanisms of hepatotoxicity.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement, Vol. 19, pp. 313-321
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The use of cultured hepatocytes to investigate the mechanisms of drug hepatotoxicity
Cell Biology and Toxicology
1996
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A microassay for measuring glycogen in 96-well-cultured cells
Analytical Biochemistry, Vol. 236, Núm. 2, pp. 296-301
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Cell cycle progression proteins (cyclins), oncogene expression, and signal transduction during the proliferative response of human hepatocytes to hepatocyte growth factor
Hepatology, Vol. 23, Núm. 5, pp. 1012-1019
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Comparative metabolism of the nonsteroidal antiinflammatory drug, aceclofenac, in the rat, monkey, and human
Drug Metabolism and Disposition, Vol. 24, Núm. 9, pp. 969-975
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Metabolism of aceclofenac in humans
Drug Metabolism and Disposition, Vol. 24, Núm. 8, pp. 834-841