Publicaciones en colaboración con investigadores/as de Centro de Investigación Biomédica en Red sobre Enfermedades Hepáticas y Digestivas (49)

2023

  1. Mechanistic Understanding of Idiosyncratic Drug-Induced Hepatotoxicity Using Co-Cultures of Hepatocytes and Macrophages

    Antioxidants, Vol. 12, Núm. 7

  2. Primary human hepatocytes-laden scaffolds for the treatment of acute liver failure

    Biomaterials Advances, Vol. 153

2022

  1. Cell models and omics techniques for the study of nonalcoholic fatty liver disease: Focusing on stem cell-derived cell models

    Antioxidants, Vol. 11, Núm. 1

  2. In Vitro Models for Studying Chronic Drug-Induced Liver Injury

    International Journal of Molecular Sciences, Vol. 23, Núm. 19

  3. Oxidative-stress and long-term hepatotoxicity: comparative study in Upcyte human hepatocytes and hepaRG cells

    Archives of Toxicology, Vol. 96, Núm. 4, pp. 1021-1037

2020

  1. Improved in vivo efficacy of clinical-grade cryopreserved human hepatocytes in mice with acute liver failure

    Cytotherapy, Vol. 22, Núm. 2, pp. 114-121

2017

  1. A multi-parametric fluorescent assay for the screening and mechanistic study of drug-induced steatosis in liver cells in culture

    Current Protocols in Toxicology, Vol. 2017, pp. 1-11

  2. Human Hepatocytes Upcytes® as in vitro experimental model to study long-term drug-induced liver injury

    Revista de Toxicologia, Vol. 34, Núm. 2, pp. 109-117

  3. Upgrading HepG2 cells with adenoviral vectors that encode drug-metabolizing enzymes: application for drug hepatotoxicity testing

    Expert Opinion on Drug Metabolism and Toxicology, Vol. 13, Núm. 2, pp. 137-148

  4. Using high-content screening technology for studying drug-induced hepatotoxicity in preclinical studies

    Expert Opinion on Drug Discovery, Vol. 12, Núm. 2, pp. 201-211

2016

  1. A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury

    Scientific Reports, Vol. 6

  2. Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis

    Toxicology and Applied Pharmacology, Vol. 302, pp. 1-9

  3. Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development

    Toxicology Letters, Vol. 263, pp. 58-67

  4. Extending metabolome coverage for untargeted metabolite profiling of adherent cultured hepatic cells

    Analytical and Bioanalytical Chemistry, Vol. 408, Núm. 4, pp. 1217-1230

  5. Human upcyte hepatocytes: Characterization of the hepatic phenotype and evaluation for acute and long-term hepatotoxicity routine testing

    Toxicological Sciences, Vol. 152, Núm. 1, pp. 214-229

  6. Metabolic activation and drug-induced liver injury: In vitro approaches for the safety risk assessment of new drugs

    Journal of Applied Toxicology, Vol. 36, Núm. 6, pp. 752-768

2015

  1. Culture and functional characterization of human hepatoma HepG2 cells

    Protocols in In Vitro Hepatocyte Research (Springer New York), pp. 77-93

  2. General cytotoxicity assessment by means of the MTT assay

    Protocols in In Vitro Hepatocyte Research (Springer New York), pp. 333-348

  3. High-content screening of drug-induced mitochondrial impairment in hepatic cells: effects of statins

    Archives of Toxicology, Vol. 89, Núm. 10, pp. 1847-1860

  4. High-content screening technology for studying drug-induced hepatotoxicity in cell models

    Archives of Toxicology, Vol. 89, Núm. 7, pp. 1007-1022