Publicaciones en colaboración con investigadores/as de Instituto de Investigación Sanitaria La Fe (37)

2023

  1. Mechanistic Understanding of Idiosyncratic Drug-Induced Hepatotoxicity Using Co-Cultures of Hepatocytes and Macrophages

    Antioxidants, Vol. 12, Núm. 7

  2. Primary human hepatocytes-laden scaffolds for the treatment of acute liver failure

    Biomaterials Advances, Vol. 153

2022

  1. Cell models and omics techniques for the study of nonalcoholic fatty liver disease: Focusing on stem cell-derived cell models

    Antioxidants, Vol. 11, Núm. 1

  2. In Vitro Models for Studying Chronic Drug-Induced Liver Injury

    International Journal of Molecular Sciences, Vol. 23, Núm. 19

  3. Oxidative-stress and long-term hepatotoxicity: comparative study in Upcyte human hepatocytes and hepaRG cells

    Archives of Toxicology, Vol. 96, Núm. 4, pp. 1021-1037

2021

  1. Application of high-content screening for the study of hepatotoxicity: Focus on food toxicology

    Food and Chemical Toxicology, Vol. 147

  2. High-content screening for the detection of drug-induced oxidative stress in liver cells

    Antioxidants, Vol. 10, Núm. 1, pp. 1-16

  3. Induced pluripotent stem cells in liver disease

    Recent Advances in iPSCs for Therapy, Volume 3: A Volume in Advances in Stem Cell Biology (Elsevier), pp. 225-250

2020

  1. Improved in vivo efficacy of clinical-grade cryopreserved human hepatocytes in mice with acute liver failure

    Cytotherapy, Vol. 22, Núm. 2, pp. 114-121

2019

  1. Long-term and mechanistic evaluation of drug-induced liver injury in Upcyte human hepatocytes

    Archives of Toxicology, Vol. 93, Núm. 2, pp. 519-532

  2. Stem-cell derived hepatocyte-like cells for the assessment of drug-induced liver injury

    Differentiation, Vol. 106, pp. 15-22

2018

  1. Assessment of the cytotoxic potential of an aqueous-ethanolic extract from Thalassia testudinum angiosperm marine grown in the Caribbean Sea

    Journal of Pharmacy and Pharmacology, Vol. 70, Núm. 11, pp. 1553-1560

  2. Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury

    Archives of Toxicology, Vol. 92, Núm. 1, pp. 383-399

2017

  1. A multi-parametric fluorescent assay for the screening and mechanistic study of drug-induced steatosis in liver cells in culture

    Current Protocols in Toxicology, Vol. 2017, pp. 1-11

  2. Human Hepatocytes Upcytes® as in vitro experimental model to study long-term drug-induced liver injury

    Revista de Toxicologia, Vol. 34, Núm. 2, pp. 109-117

  3. In vitro modulation of the cytochrome P450 and ABCB1/P-glycoprotein activities of the aqueous extract of Allophylus cominia (L) Sw. leaves

    Drug Metabolism and Personalized Therapy, Vol. 32, Núm. 4, pp. 201-208

  4. Upgrading HepG2 cells with adenoviral vectors that encode drug-metabolizing enzymes: application for drug hepatotoxicity testing

    Expert Opinion on Drug Metabolism and Toxicology, Vol. 13, Núm. 2, pp. 137-148

  5. Using high-content screening technology for studying drug-induced hepatotoxicity in preclinical studies

    Expert Opinion on Drug Discovery, Vol. 12, Núm. 2, pp. 201-211

2016

  1. Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis

    Toxicology and Applied Pharmacology, Vol. 302, pp. 1-9

  2. Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development

    Toxicology Letters, Vol. 263, pp. 58-67