Publikationen, an denen er mitarbeitet JOSE VICENTE CASTELL RIPOLL (103)

2020

  1. Improved in vivo efficacy of clinical-grade cryopreserved human hepatocytes in mice with acute liver failure

    Cytotherapy, Vol. 22, Núm. 2, pp. 114-121

2019

  1. Long-term and mechanistic evaluation of drug-induced liver injury in Upcyte human hepatocytes

    Archives of Toxicology, Vol. 93, Núm. 2, pp. 519-532

2018

  1. Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury

    Archives of Toxicology, Vol. 92, Núm. 1, pp. 383-399

2016

  1. A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury

    Scientific Reports, Vol. 6

  2. Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development

    Toxicology Letters, Vol. 263, pp. 58-67

  3. Extending metabolome coverage for untargeted metabolite profiling of adherent cultured hepatic cells

    Analytical and Bioanalytical Chemistry, Vol. 408, Núm. 4, pp. 1217-1230

  4. Human upcyte hepatocytes: Characterization of the hepatic phenotype and evaluation for acute and long-term hepatotoxicity routine testing

    Toxicological Sciences, Vol. 152, Núm. 1, pp. 214-229

2015

  1. High-content screening of drug-induced mitochondrial impairment in hepatic cells: effects of statins

    Archives of Toxicology, Vol. 89, Núm. 10, pp. 1847-1860

  2. Human neonatal hepatocyte transplantation induces long-term rescue of unconjugated hyperbilirubinemia in the Gunn rat

    Liver Transplantation, Vol. 21, Núm. 6, pp. 801-811

  3. LC-MS untargeted metabolomic analysis of drug-induced hepatotoxicity in HepG2 cells

    Electrophoresis, Vol. 36, Núm. 18, pp. 2294-2302

  4. Repression of the nuclear receptor small heterodimer partner by steatotic drugs and in advanced nonalcoholic fatty liver disease

    Molecular Pharmacology, Vol. 87, Núm. 4, pp. 582-594

2014

  1. A simple transcriptomic signature able to predict drug-induced hepatic steatosis

    Archives of Toxicology, Vol. 88, Núm. 4, pp. 967-982

  2. Metabolomics discloses donor liver biomarkers associated with early allograft dysfunction

    Journal of Hepatology, Vol. 61, Núm. 3, pp. 564-574

  3. Neonatal livers: A source for the isolation of good-performing hepatocytes for cell transplantation

    Cell Transplantation, Vol. 23, Núm. 10, pp. 1229-1242

2013

  1. HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: Identification of bioactivable drugs and the potential mechanism of toxicity involved

    Archives of Toxicology, Vol. 87, Núm. 6, pp. 1115-1127

  2. Mangifera indica L. extract and mangiferin modulate cytochrome P450 and UDP-glucuronosyltransferase enzymes in primary cultures of human hepatocytes

    Phytotherapy Research, Vol. 27, Núm. 5, pp. 745-752

  3. Multiparametric evaluation of the cytoprotective effect of the Mangifera indica L. stem bark extract and mangiferin in HepG2 cells

    Journal of Pharmacy and Pharmacology, Vol. 65, Núm. 7, pp. 1073-1082

2012

  1. Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs

    Toxicological Sciences, Vol. 127, Núm. 1, pp. 187-198

  2. Evaluation of cytochrome P450 activities in human hepatocytes in vitro

    Methods in Molecular Biology, Vol. 806, pp. 87-97

  3. High-content imaging technology for the evaluation of drug-induced steatosis using a multiparametric cell-based assay

    Journal of Biomolecular Screening, Vol. 17, Núm. 3, pp. 394-400