Publicaciones en colaboración con investigadores/as de Hospital Clinico Universitario de Valencia (20)

2024

  1. Benzopyran hydrazones with dual PPARα/γ or PPARα/δ agonism and an anti-inflammatory effect on human THP-1 macrophages

    European Journal of Medicinal Chemistry, Vol. 265

  2. Synthesis of a new 2-prenylated quinoline as potential drug for metabolic syndrome with pan-PPAR activity and anti-inflammatory effects

    Bioorganic and Medicinal Chemistry Letters, Vol. 106

2023

  1. Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity

    Pharmacological Research, Vol. 187

  2. Synthesis of 2-aminopropyl benzopyran derivatives as potential agents against triple-negative breast cancer

    RSC Medicinal Chemistry, Vol. 14, Núm. 11, pp. 2327-2341

2022

  1. Synthesis and biological studies of “Polycerasoidol” and “trans-δ-Tocotrienolic acid” derivatives as PPARα and/or PPARγ agonists

    Bioorganic and Medicinal Chemistry, Vol. 53

2021

  1. Natural products and analogs as preventive agents for metabolic syndrome via peroxisome proliferator-activated receptors: An overview

    European Journal of Medicinal Chemistry, Vol. 221

  2. Synthesis of 2-Prenylated Alkoxylated Benzopyrans by Horner-Wadsworth-Emmons Olefination with PPARα/γAgonist Activity

    ACS Medicinal Chemistry Letters, Vol. 12, Núm. 11, pp. 1783-1786

2020

  1. 1-(2′-Bromobenzyl)-6,7-dihydroxy- N-methyl-tetrahydroisoquinoline and 1,2-Demethyl-nuciferine as Agonists in Human D2 Dopamine Receptors

    Journal of Natural Products, Vol. 83, Núm. 1, pp. 127-133

  2. Acetogenins from Annonaceae family. Their potential biological applications

    Phytochemistry, Vol. 174

2019

  1. Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPARα/PPARγAgonist Activity and Anti-inflammatory Effect

    Journal of Natural Products, Vol. 82, Núm. 7, pp. 1802-1812

  2. Synthesis of benzopyran derivatives as PPARα and/or PPARγ activators

    Bioorganic and Medicinal Chemistry, Vol. 27, Núm. 24

2017

  1. Tetrahydroisoquinolines functionalized with carbamates as selective ligands of D2 dopamine receptor

    Journal of Molecular Modeling, Vol. 23, Núm. 9

2016

  1. Dopaminergic isoquinolines with hexahydrocyclopenta[ ij ]-isoquinolines as D2-like selective ligands

    European Journal of Medicinal Chemistry, Vol. 122, pp. 27-42

2015

  1. Synthesis and antibacterial activities of cadiolides A, B and C and analogues

    Bioorganic and Medicinal Chemistry, Vol. 23, Núm. 13, pp. 3618-3628

  2. Synthesis of hexahydrocyclopenta[ ij[isoquinolines as a new class of dopaminergic agents

    European Journal of Medicinal Chemistry, Vol. 90, pp. 101-106

2014

  1. Efficient synthesis of hexahydroindenopyridines and their potential as melatoninergic ligands

    European Journal of Medicinal Chemistry, Vol. 86, pp. 700-709

2013

  1. 2,3,9- and 2,3,11-Trisubstituted tetrahydroprotoberberines as D2 dopaminergic ligands

    European Journal of Medicinal Chemistry, Vol. 68, pp. 150-166

  2. 3,4-Dihydroxy- and 3,4-methylenedioxy- phenanthrene-type alkaloids with high selectivity for D2 dopamine receptor

    Bioorganic and Medicinal Chemistry Letters, Vol. 23, Núm. 17, pp. 4824-4827

  3. Novel isoquinoline derivatives as antimicrobial agents

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 11, pp. 3221-3230

  4. Synthesis of pyrido[2,1-a]isoquinolin-4-ones and oxazino[2,3-a]isoquinolin- 4-ones: New inhibitors of mitochondrial respiratory chain

    European Journal of Medicinal Chemistry, Vol. 69, pp. 69-76