Publications by the researcher in collaboration with José Tormo Iguacel (19)

2013

  1. Analysis of cytotoxic activity at short incubation times reveals profound differences among Annonaceus acetogenins, inhibitors of mitochondrial Complex i

    Journal of Bioenergetics and Biomembranes, Vol. 45, Núm. 1-2, pp. 145-152

2007

  1. New antitumoral acetogenin 'Guanacone type' derivatives: Isolation and bioactivity. Molecular dynamics simulation of diacetyl-guanacone

    Bioorganic and Medicinal Chemistry, Vol. 15, Núm. 13, pp. 4369-4381

2006

  1. Guanaconetins, new antitumoral acetogenins, mitochondrial complex I and tumor cell growth inhibitors

    Bioorganic and Medicinal Chemistry, Vol. 14, Núm. 4, pp. 1089-1094

2005

  1. In vitro antitumor structure-activity relationships of threo/trans/threo/ trans/erythro bis-Tetrahydrofuranic acetogenins: Correlations with their inhibition of mitochondrial complex I

    Oncology Research, Vol. 15, Núm. 3, pp. 129-138

2003

  1. In Vitro Antitumor Structure-Activity Relationships of threo/trans/threo mono-Tetrahydrofuranic Acetogenins: Correlations with Their Inhibition of Mitochondrial Complex I

    Oncology Research, Vol. 14, Núm. 3, pp. 147-154

  2. Inhibitory effects on mitochondrial complex I of semisynthetic mono-tetrahydrofuran acetogenin derivatives

    Bioorganic and Medicinal Chemistry Letters, Vol. 13, Núm. 22, pp. 4101-4105

2002

  1. In Vitro Antitumor SAR of threo/cis/threo/cis/erythro bis-THF Acetogenins: Correlations with Their Inhibition of Mitochondrial Complex I

    Oncology Research, Vol. 13, Núm. 12, pp. 521-528

2001

  1. γ-lactone-functionalized antitumoral acetogenins are the most potent inhibitors of mitochondrial complex I

    Bioorganic and Medicinal Chemistry Letters, Vol. 11, Núm. 5, pp. 681-684

2000

  1. Epoxy-acetogenins and other polyketide epoxy derivatives as inhibitors of the mitochondrial respiratory chain complex I

    Planta Medica, Vol. 66, Núm. 4, pp. 318-323

  2. Semisynthesis of antitumoral acetogenins: SAR of functionalized alkyl-chain bis-tetrahydrofuranic acetogenins, specific inhibitors of mitochondrial complex I

    Journal of Medicinal Chemistry, Vol. 43, Núm. 25, pp. 4793-4800

  3. Synthesis of N-diisopropyl phosphoryl benzyl-tetrahydroisoquinoline, a new class of mitochondrial complexes I and III inhibitors

    Bioorganic and Medicinal Chemistry Letters, Vol. 10, Núm. 13, pp. 1491-1494

1999

  1. Kinetic characterization of mitochondrial complex I inhibitors using annonaceous acetogenins

    Archives of Biochemistry and Biophysics, Vol. 369, Núm. 1, pp. 119-126

  2. Specific interactions of monotetrahydrofuranic annonaceous acetogenins as inhibitors of mitochondrial complex I

    Chemico-Biological Interactions, Vol. 122, Núm. 3, pp. 171-183

1998

  1. 10-oximeguanacone, the first nitrogenated acetogenin derivative found to be a potent inhibitor of mitochondrial complex I

    Journal of Natural Products, Vol. 61, Núm. 8, pp. 1001-1005

  2. Acetogenins from Annona glabra seeds

    Phytochemistry, Vol. 47, Núm. 5, pp. 811-816

  3. Natural acetogenins from annonaceae, synthesis and mechanisms of action

    Phytochemistry, Vol. 48, Núm. 7, pp. 1087-1117

1997

  1. Cherimolin-1, new selective inhibitor of the first energy-coupling site of the NADH:ubiquinone oxidoreductase (Complex I)

    Biochemical and Biophysical Research Communications, Vol. 240, Núm. 1, pp. 234-238

  2. Rollimembrin, a novel acetogenin inhibitor of mammalian mitochondrial complex I

    Bioorganic and Medicinal Chemistry Letters, Vol. 7, Núm. 9, pp. 1113-1118

1996

  1. Polyalthidin: New prenylated benzopyran inhibitor of the mammalian mitochondrial respiratory chain

    Journal of Natural Products, Vol. 59, Núm. 10, pp. 913-916