Publicaciones en colaboración con investigadores/as de Centro de Investigaciones Biológicas (8)

2021

  1. Synthesis of N-acyl derivatives of aminocombretastatin A-4 and study of their interaction with tubulin and downregulation of c-Myc

    Medicinal Chemistry, Vol. 17, Núm. 10, pp. 1129-1139

2015

  1. The Mechanism of the Interactions of Pironetin Analog/Combretastatin A-4 Hybrids with Tubulin

    Archiv der Pharmazie, Vol. 348, Núm. 8, pp. 541-547

2014

  1. Design and synthesis of pironetin analogue/colchicine hybrids and study of their cytotoxic activity and mechanisms of interaction with tubulin

    Journal of Medicinal Chemistry, Vol. 57, Núm. 24, pp. 10391-10403

2013

  1. Synthesis and biological evaluation as microtubule-active agents of several tetrahydrofuran and spiroacetal derivatives

    Current Medicinal Chemistry, Vol. 20, Núm. 9, pp. 1173-1182

  2. Synthesis and biological evaluation of truncated α-tubulin-binding pironetin analogues lacking alkyl pendants in the side chain or the dihydropyrone ring

    Organic and Biomolecular Chemistry, Vol. 11, Núm. 35, pp. 5809-5826

  3. Synthesis and biological evaluation of α-tubulin-binding pironetin analogues with enhanced lipophilicity

    European Journal of Organic Chemistry, pp. 1116-1123

2011

  1. Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 5, pp. 1630-1637

2007

  1. The total synthesis and biological properties of the cytotoxic macrolide FD-891 and its non-natural (Z)-C12 isomer

    Chemistry - A European Journal, Vol. 13, Núm. 18, pp. 5060-5074