MATILDE
MERINO SANJUAN
CATEDRÁTICO/A DE UNIVERSIDAD
Universidad Miguel Hernández de Elche
Elche, EspañaPublications en collaboration avec des chercheurs de Universidad Miguel Hernández de Elche (15)
2019
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Ion-pair approach coupled with nanoparticle formation to increase bioavailability of a low permeability charged drug
International Journal of Pharmaceutics, Vol. 557, pp. 36-42
2018
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Closed-Loop Doluisio (Colon, Small Intestine) and Single-Pass Intestinal Perfusion (Colon, Jejunum) in Rat—Biophysical Model and Predictions Based on Caco-2
Pharmaceutical Research, Vol. 35, Núm. 1
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Defining level A IVIVC dissolution specifications based on individual in vitro dissolution profiles of a controlled release formulation
European Journal of Pharmaceutical Sciences, Vol. 119, pp. 200-207
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PLGA nanoparticles are effective to control the colonic release and absorption on ibuprofen
European Journal of Pharmaceutical Sciences, Vol. 115, pp. 119-125
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Preclinical models for colonic absorption, application to controlled release formulation development
European Journal of Pharmaceutics and Biopharmaceutics, Vol. 130, pp. 247-259
2017
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Comparison of segmental-dependent permeability in human and in situ perfusion model in rat
European Journal of Pharmaceutical Sciences, Vol. 107, pp. 191-196
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IVIVC approach based on carbamazepine bioequivalence studies combination
Pharmazie, Vol. 72, Núm. 8, pp. 449-455
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Investigating drug absorption from the colon: Single-pass vs. Doluisio approaches to in-situ rat large-intestinal perfusion
International Journal of Pharmaceutics, Vol. 527, Núm. 1-2, pp. 135-141
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Usefulness of Caco-2/HT29-MTX and Caco-2/HT29-MTX/Raji B coculture models to predict intestinal and colonic permeability compared to Caco-2 monoculture
Molecular Pharmaceutics, Vol. 14, Núm. 4, pp. 1264-1270
2016
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Development of an ion-pair to improve the colon permeability of a low permeability drug: Atenolol
European Journal of Pharmaceutical Sciences, Vol. 93, pp. 334-340
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Segmental-dependent permeability throughout the small intestine following oral drug administration: Single-pass vs. Doluisio approach to in-situ rat perfusion
International Journal of Pharmaceutics, Vol. 515, Núm. 1-2, pp. 201-208
2015
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In Situ Perfusion Model in Rat Colon for Drug Absorption Studies: Comparison with Small Intestine and Caco-2 Cell Model
Journal of Pharmaceutical Sciences, Vol. 104, Núm. 9, pp. 3136-3145
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In vitro-in vivo correlations: General concepts, methodologies and regulatory applications
Drug Development and Industrial Pharmacy, Vol. 41, Núm. 12, pp. 1935-1947
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In-situ intestinal rat perfusions for human Fabs prediction and BCS permeability class determination: Investigation of the single-pass vs. the Doluisio experimental approaches
International Journal of Pharmaceutics, Vol. 480, Núm. 1-2, pp. 1-7
2007
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Stability studies of binary mixtures of haloperidol and/or midazolam with other drugs for parenteral administration
Journal of Palliative Medicine, Vol. 10, Núm. 6, pp. 1306-1311