ANGEL LUIS
ORTEGA VALERO
TITULAR DE UNIVERSIDAD
M ELENA
OBRADOR PLA
CATEDRÁTICO/A DE UNIVERSIDAD
Publicacions en què col·labora amb M ELENA OBRADOR PLA (16)
2016
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Glutathione in metastases: From mechanisms to clinical applications
Critical Reviews in Clinical Laboratory Sciences, Vol. 53, Núm. 4, pp. 253-267
2015
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Astrocytes protect neurons from Aβ1-42 peptide-induced neurotoxicity increasing TFAM and PGC-1 and decreasing PPAR-γ and SIRT-1
International Journal of Medical Sciences, Vol. 12, Núm. 1, pp. 48-56
2012
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Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1
Journal of Translational Medicine, Vol. 10, Núm. 1
2008
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Natural polyphenols facilitate elimination of HT-29 colorectal cancer xenografts by chemoradiotherapy: A Bcl-2- and superoxide dismutase 2-dependent mechanism
Molecular Cancer Therapeutics, Vol. 7, Núm. 10, pp. 3330-3342
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Tumoricidal activity of endothelium-derived NO and the survival of metastatic cells with high GSH and Bcl-2 levels
Nitric Oxide - Biology and Chemistry, Vol. 19, Núm. 2, pp. 107-114
2007
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Bcl-2 and glutathione depletion sensitizes B16 melanoma to combination therapy and eliminates metastatic disease
Clinical Cancer Research, Vol. 13, Núm. 9, pp. 2658-2666
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Nitric oxide mediates natural polyphenol-induced Bcl-2 down-regulation and activation of cell death in metastatic B16 melanoma
Journal of Biological Chemistry, Vol. 282, Núm. 5, pp. 2880-2890
2006
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Bcl-2 and Mn-SOD antisense oligodeoxynucleotides and a glutamine-enriched diet facilitate elimination of highly resistant B16 melanoma cells by tumor necrosis factor-α and chemotherapy
Journal of Biological Chemistry, Vol. 281, Núm. 1, pp. 69-79
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Glutathione in cancer biology and therapy
Critical Reviews in Clinical Laboratory Sciences, Vol. 43, Núm. 2, pp. 143-181
2005
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Acceleration of glutathione efflux and inhibition of γ- glutamyltranspeptidase sensitize metastatic B16 melanoma cells to endothelium-induced cytotoxicity
Journal of Biological Chemistry, Vol. 280, Núm. 8, pp. 6950-6959
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Association between pterostilbene and quercetin inhibits metastatic activity of B16 melanoma
Neoplasia, Vol. 7, Núm. 1, pp. 37-47
2003
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Down-regulation of glutathione and Bcl-2 synthesis in mouse B16 melanoma cells avoids their survival during interaction with the vascular endothelium
Journal of Biological Chemistry, Vol. 278, Núm. 41, pp. 39591-39599
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Tumor cytotoxicity by endothelial cells: Impairment of the mitochondrial system for glutathione uptake in mouse B16 melanoma cells that survive after in vitro interaction with the hepatic sinusoidal endothelium
Journal of Biological Chemistry, Vol. 278, Núm. 16, pp. 13888-13897
2002
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Inhibition of cancer growth by resveratrol is related to its low bioavailability
Free Radical Biology and Medicine, Vol. 33, Núm. 3, pp. 387-398
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γ-glutamyl transpeptidase overexpression increases metastatic growth of B16 melanoma cells in the mouse liver
Hepatology, Vol. 35, Núm. 1, pp. 74-81
2001
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Tumoricidal activity of endothelial cells: Inhibition of endothelial nitric oxide production abrogates tumor cytotoxicity induced by hepatic sinusoidal endothelium in response to B16 melanoma adhesion in vitro
Journal of Biological Chemistry, Vol. 276, Núm. 28, pp. 25775-25782