Publications en collaboration avec des chercheurs de Harvard Medical School (13)

2017

  1. Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade

    Journal of Thoracic Oncology, Vol. 12, Núm. 8, pp. 1268-1279

2016

  1. Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung cancer

    Cancer Discovery, Vol. 6, Núm. 9, pp. 1007-1021

2015

  1. Expression inactivation of SMARCA4 by microRNAs in lung tumors

    Human Molecular Genetics, Vol. 24, Núm. 5, pp. 1400-1409

2014

  1. D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice

    Genes and Development, Vol. 28, Núm. 5, pp. 479-490

  2. Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor

    Cancer Cell, Vol. 26, Núm. 6, pp. 909-922

  3. β-catenin contributes to lung tumor development induced by EGFR mutations

    Cancer Research, Vol. 74, Núm. 20, pp. 5891-5902

2013

  1. Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors

    Cancer Discovery, Vol. 3, Núm. 12, pp. 1355-1363

  2. Efficacy of BET bromodomain inhibition in KRAS-mutant non-small cell lung cancer

    Clinical Cancer Research, Vol. 19, Núm. 22, pp. 6183-6192

  3. Loss of p53 attenuates the contribution of IL-6 deletion on suppressed tumor progression and extended survival in Kras-driven murine lung cancer

    PLoS ONE, Vol. 8, Núm. 11

  4. Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1 -mutant lung cancer

    Cancer Discovery, Vol. 3, Núm. 8, pp. 870-879

2012

  1. Ganetespib (STA-9090), a nongeldanamycin HSP90 inhibitor, has potent antitumor activity in in vitro and in vivo models of non-small cell lung cancer

    Clinical Cancer Research, Vol. 18, Núm. 18, pp. 4973-4985

  2. Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Núm. 22, pp. 8699-8704

2010

  1. Inhibition of ALK, PI3K/MEK, and HSP90 in murine lung adenocarcinoma induced by EML4-ALK fusion oncogene

    Cancer Research, Vol. 70, Núm. 23, pp. 9827-9836