JOSE MANUEL
TORRES IBAÑEZ
PROF. PERMANENTE LABORAL PPL
Centro de Investigación Príncipe Felipe
Valencia, EspañaCentro de Investigación Príncipe Felipe -ko ikertzaileekin lankidetzan egindako argitalpenak (15)
2023
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Rapid degeneration of iPSC-derived motor neurons lacking Gdap1 engages a mitochondrial-sustained innate immune response
Cell Death Discovery, Vol. 9, Núm. 1
2021
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A High-Throughput Chemical Screen in DJ-1β Mutant Flies Identifies Zaprinast as a Potential Parkinson’s Disease Treatment
Neurotherapeutics, Vol. 18, Núm. 4, pp. 2565-2578
2018
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MYC Induces a Hybrid Energetics Program Early in Cell Reprogramming
Stem Cell Reports, Vol. 11, Núm. 6, pp. 1479-1492
2017
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Generation of a disease-specific iPS cell line derived from a patient with Charcot-Marie-Tooth type 2K lacking functional GDAP1 gene
Stem Cell Research, Vol. 18, pp. 1-4
2016
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Dysfunctional mitochondrial fission impairs cell reprogramming
Cell Cycle, Vol. 15, Núm. 23, pp. 3240-3250
2006
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Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs
Molecular Biology of the Cell, Vol. 17, Núm. 9, pp. 4002-4013
2005
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Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases
Journal of Biological Chemistry, Vol. 280, Núm. 32, pp. 28936-28943
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Functional definition of relevant epitopes on the tumor suppressor PTEN protein
Cancer Letters, Vol. 223, Núm. 2, pp. 303-312
2004
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Regulation of MAPK cascades by protein tyrosine phosphatases.
Methods in molecular biology (Clifton, N.J.), Vol. 250, pp. 103-112
2003
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A Novel Loss-of-Function Mutation (N48K) in the PTEN Gene in a Spanish Patient with Cowden Disease
Journal of Investigative Dermatology, Vol. 121, Núm. 6, pp. 1356-1359
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Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3. Implications for the control of protein stability and PTEN-protein interactions
Journal of Biological Chemistry, Vol. 278, Núm. 33, pp. 30652-30660
2001
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Heterogeneous lack of expression of the tumour suppressor PTEN protein in human neoplastic tissues
European Journal of Cancer, Vol. 37, Núm. 1, pp. 114-121
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The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation
Journal of Biological Chemistry, Vol. 276, Núm. 2, pp. 993-998
1999
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A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase
Journal of Cell Biology, Vol. 147, Núm. 6, pp. 1129-1135
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Interaction of mitogen-activated protein kinases with the kinase interaction motif of the tyrosine phosphatase PTP-SL provides substrate specificity and retains ERK2 in the cytoplasm
Journal of Biological Chemistry, Vol. 274, Núm. 31, pp. 21900-21907