Publications en collaboration avec des chercheurs de Universidad Nacional de San Luis (17)

2024

  1. Benzopyran hydrazones with dual PPARα/γ or PPARα/δ agonism and an anti-inflammatory effect on human THP-1 macrophages

    European Journal of Medicinal Chemistry, Vol. 265

  2. Synthesis of a new 2-prenylated quinoline as potential drug for metabolic syndrome with pan-PPAR activity and anti-inflammatory effects

    Bioorganic and Medicinal Chemistry Letters, Vol. 106

2023

  1. Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity

    Pharmacological Research, Vol. 187

2021

  1. Design, synthesis, biological evaluation and molecular modelling of substituted pyrrolo[2,1-: A] isoquinolinone derivatives: Discovery of potent inhibitors of AChE and BChE

    New Journal of Chemistry, Vol. 45, Núm. 18, pp. 8321-8334

2019

  1. Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPARα/PPARγAgonist Activity and Anti-inflammatory Effect

    Journal of Natural Products, Vol. 82, Núm. 7, pp. 1802-1812

  2. Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti-inflammatory activity

    Archiv der Pharmazie, Vol. 352, Núm. 3

2016

  1. Dopaminergic isoquinolines with hexahydrocyclopenta[ ij ]-isoquinolines as D2-like selective ligands

    European Journal of Medicinal Chemistry, Vol. 122, pp. 27-42

2015

  1. 3-chlorotyramine acting as ligand of the D2 dopamine receptor. Molecular modeling, synthesis and D2 receptor affinity

    Molecular Informatics, Vol. 34, Núm. 1, pp. 28-43

2013

  1. 2,3,9- and 2,3,11-Trisubstituted tetrahydroprotoberberines as D2 dopaminergic ligands

    European Journal of Medicinal Chemistry, Vol. 68, pp. 150-166

2012

  1. Searching the "biologically relevant" conformation of dopamine: A computational approach

    Journal of Chemical Information and Modeling, Vol. 52, Núm. 1, pp. 99-112

  2. Tetrahydroisoquinolines acting as dopaminergic ligands. A molecular modeling study using MD simulations and QM calculations

    Journal of Molecular Modeling, Vol. 18, Núm. 2, pp. 419-431

2009

  1. Structure-activity relationship of dopaminergic halogenated 1-benzyl-tetrahydroisoquinoline derivatives

    European Journal of Medicinal Chemistry, Vol. 44, Núm. 11, pp. 4616-4621

  2. Tetrahydroisoquinolines as dopaminergic ligands: 1-Butyl-7-chloro-6-hydroxy-tetrahydroisoquinoline, a new compound with antidepressant-like activity in mice

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 14, pp. 4968-4980

2007

  1. New antitumoral acetogenin 'Guanacone type' derivatives: Isolation and bioactivity. Molecular dynamics simulation of diacetyl-guanacone

    Bioorganic and Medicinal Chemistry, Vol. 15, Núm. 13, pp. 4369-4381

2006

  1. Efficient synthesis and structural analysis of new dioxopiperazine isoquinolines

    Tetrahedron, Vol. 62, Núm. 18, pp. 4408-4418

2003

  1. Molecular recognition and binding mechanism of N-alkyl- benzyltetrahydroisoquinolines to the D1 dopamine receptor. A computational approach

    Journal of Molecular Structure: THEOCHEM

2002

  1. Syntheses and antitumor targeting G1 phase of the cell cycle of benzoyldihydroisoquinolines and related 1-substituted isoquinolines

    Journal of Medicinal Chemistry, Vol. 45, Núm. 23, pp. 5058-5068