A novel UPLC-MS metabolomic analysis-based strategy to monitor the course and extent of iPSC differentiation to hepatocytes

  1. Moreno-Torres, Marta 1
  2. Kumar, Manoj 2
  3. Llorens, Guillem García 3
  4. Quintás, Guillermo 4
  5. Tricot, Tine 2
  6. Boon, Ruben 5
  7. Tolosa, Laia 1
  8. Toprakhisar, Burak 2
  9. Francois Chesnais 6
  10. Verfaillie, Catherine 2
  11. Castell, José V. 7
  1. 1 Unidad de Hepatología Experimental, Health Research Institute Hospital La Fe, Valencia, Spain
  2. 2 Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium
  3. 3 Unidad de Hepatología Experimental, Health Research Institute Hospital La Fe, Valencia, Spain &Departamento de Bioquímica y Biología Molecular, Universidad de Valencia, Valencia, Spain
  4. 4 Health and Biomedicine, LEITAT Technological Center, Barcelona, Spain &Analytical Unit, Health Research Institute Hospital La Fe, Valencia, Spain
  5. 5 Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium &Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts 02114, USA & The Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA
  6. 6 Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium &Academic Center of Reconstructive Science, Kings College London, London
  7. 7 Unidad de Hepatología Experimental, Health Research Institute Hospital La Fe, Valencia, Spain &Analytical Unit, Health Research Institute Hospital La Fe, Valencia, Spain &Departamento de Bioquímica y Biología Molecular, Universidad de Valencia, Valencia, Spain &Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain
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Verleger: Zenodo

Datum der Publikation: 2021

Art: Dataset

CC BY 4.0

DOI: 10.5281/ZENODO.4922509 lock_openOpen Access editor

Zusammenfassung

ms2 raw data, peak tables generated in Quantitative Analysis Software from Agilent and Matlab functions for QC-SVRC, data clean-up and analysis for the publication with title "Monitoring the differentiation of iPSC to hepatocytes by means of UPLC-MS metabolomics".