Cáncer y fertilidad

  1. Begoña Bermejo 1
  2. Blanca Navarro 1
  3. Ana Lluch 1
  1. 1 Hospital Clínico Universitario de Valencia, España
Aldizkaria:
Arbor: Ciencia, pensamiento y cultura

ISSN: 0210-1963

Argitalpen urtea: 2015

Zenbakien izenburua: Mujer y cancer

Zenbakia: 773

Mota: Artikulua

DOI: 10.3989/ARBOR.2015.773N3009 DIALNET GOOGLE SCHOLAR lock_openSarbide irekia editor

Beste argitalpen batzuk: Arbor: Ciencia, pensamiento y cultura

Laburpena

The sociological changes occurring in recent decades have led to women having their first child much later than in the past. On the other hand, the early diagnosis of some tumors, such as breast or cervix, and the advances made in oncological treatments have achieved very favorable cure rates. All these aspects lead to the fact that women, whose chances of surviving this disease are improving all the time, wish to fulfill their wish to have children, which is going to be frequently lessened due to the treatments received. Having children is an important part of life for many people, and clinicians (oncologists, surgeons, gynecologists, etc.) must inform the patient properly about the risks that the process entails regarding fertility, as well as explaining the different options to preserve it. In this article, we will discuss fertility in women only, how it is affected, and how to protect it.

Erreferentzia bibliografikoak

  • Blumenfeld, Z. (2007). How to preserve fertility in young women exposed to chemotherapy? The role of GnRH agonist cotreatment in addition to cryopreservation of embrya, oocytes, or ovaries. Oncologist, 12, 9, pp. 1044-1054. http://dx.doi.org/10.1634/theoncologist.12-9-1044 PMid:17914074
  • Callejo, J., Salvador, C., Gonzalez-Nunez, S., Almeida, L., Rodriguez, L., Marques, L. et al. (2013). Live birth in a woman without ovaries after autograft of frozen-thawed ovarian tissue combined with growth factors. Journal of Ovarian Research, 6, 1, pp. 33. http://dx.doi.org/10.1186/1757-2215-6-33 PMid:23647552 PMCid:PMC3674930
  • Cobo, A., Domingo, J., Perez, S., Crespo, J., Remohi, J. y Pellicer, A. (2008). Vitrification: an effective new approach to oocyte banking and preserving fertility in cancer patients. Clinical and Translational Oncology, 10, 5, pp. 268-273. http://dx.doi.org/10.1007/s12094-008-0196-7
  • Cobo, A., Garcia-Velasco, J. A., Domingo, J., Remohi, J. y Pellicer, A. (2013). Is vitrification of oocytes useful for fertility preservation for age-related fertility decline and in cancer patients? Fertility and Sterility, 99, 6, pp. 1485-1495.
  • Del Mastro, L., Boni, L., Michelotti, A., Gamucci, T., Olmeo, N., Gori, S. et al. (2011). Effect of the gonadotropin-releasing hormone analogue triptorelin on the occurrence of chemotherapy-induced early menopause in premenopausal women with breast cancer: a randomized trial. Journal of the American Association, 306, 3, pp. 269-276. http://dx.doi.org/10.1001/jama.2011.991
  • Donnez, J., Dolmans, M. M., Pellicer, A., Diaz-Garcia, C., Sanchez Serrano, M., Schmidt, K. T. et al. (2013). Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation. Fertility and Sterility, 99, 6, pp. 1503-1513. http://dx.doi.org/10.1016/j.fertnstert.2013.03.030 PMid:23635349
  • Hickey, M., Peate, M., Saunders, C. M. y Friedlander, M. (2009). Breast cancer in young women and its impact on reproductive function. Human Reproduction Update, 15, 3, pp. 323-339. http://dx.doi.org/10.1093/humupd/dmn064 PMid:19174449 PMCid:PMC2667113
  • Kishk, E. A. y Mohammed Ali, M. H. (2013). Effect of a gonadotropin-releasing hormone analogue on cyclophosphamide-induced ovarian toxicity in adult mice. Archives of Gynecology and Obstetrics, 287, 5, pp. 1023-1029. http://dx.doi.org/10.1007/s00404-012-2658-y PMid:23224696
  • Lee, S. J., Schover, L. R., Partridge, A. H., Patrizio, P., Wallace, W. H., Hagerty, K. et al. (2006). American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. Journal of Clinical Oncology, 24, 18, pp. 2917-2931. http://dx.doi.org/10.1200/JCO.2006.06.5888 PMid:16651642
  • Loren, A. W., Mangu, P. B., Beck, L. N., Brennan, L., Magdalinski, A. J., Partridge, A. H. et al. (2013). Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. Journal of Clinical Oncology, 31, 19, pp. 2500-2510. http://dx.doi.org/10.1200/JCO.2013.49.2678 PMid:23715580
  • Meirow, D., Hardan, I., Dor, J., Fridman, E., Elizur, S., Ra'anani, H. et al. (2008). Searching for evidence of disease and malignant cell contamination in ovarian tissue stored from hematologic cancer patients. Human Reproduction, 23, 5, pp. 1007-1013. http://dx.doi.org/10.1093/humrep/den055 PMid:18344563
  • Peccatori, F. A., Azim, H. A., Jr., Orecchia, R., Hoekstra, H. J., Pavlidis, N., Kesic, V. et al. (2013). Cancer, pregnancy and fertility: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology, 24 Suppl 6, pp. vi160-170. http://dx.doi.org/10.1093/annonc/mdt199 PMid:23813932
  • Reddy, J. y Oktay, K. (2012). Ovarian stimulation and fertility preservation with the use of aromatase inhibitors in women with breast cancer. Fertility and Sterility, 98, 6, pp. 1363-1369. http://dx.doi.org/10.1016/j.fertnstert.2012.09.022 PMid:23058686
  • Ruddy, K. J., Guo, H., Barry, W., Dang, C. T., Yardley, D. A., Moy, B. et al. (2015). Chemotherapy-related amenorrhea after adjuvant paclitaxel-trastuzumab (APT trial). Breast Cancer Research and Treatment, 151, 3, pp. 589-596. http://dx.doi.org/10.1007/s10549-015-3426-z PMid:25981899
  • Sanchez-Serrano, M., Novella-Maestre, E., Rosello-Sastre, E., Camarasa, N., Teruel, J. y Pellicer, A. (2009). Malignant cells are not found in ovarian cortex from breast cancer patients undergoing ovarian cortex cryopreservation. Human Reproduction, 24, 9, pp. 2238-2243. http://dx.doi.org/10.1093/humrep/dep196 PMid:19491203
  • Siegel, R., Ma, J., Zou, Z. y Jemal, A. (2014). Cancer statistics, 2014. CA A Cancer Journal for Clinicians, 64, 1, pp. 9-29. http://dx.doi.org/10.3322/caac.21208 PMid:24399786
  • Sonmezer, M. y Oktay, K. (2006). Fertility preservation in young women undergoing breast cancer therapy. Oncologist, 11, 5, pp. 422-434. http://dx.doi.org/10.1634/theoncologist.11-5-422 PMid:16720842
  • Zamah, A. M., Mauro, M. J., Druker, B. J., Oktay, K., Egorin, M. J., Cedars, M. I. et al. (2011). Will imatinib compromise reproductive capacity? Oncologist, 16, 10, pp. 1422-1427.