Psychophysiological response to social stressorsRelevance of sex and age

  1. Matias M. Pulopulos 3
  2. Vanesa Hidalgo 1
  3. Sara Puig-Pérez 2
  4. Alicia Salvador 2
  1. 1 Universidad de Zaragoza
    info

    Universidad de Zaragoza

    Zaragoza, España

    ROR https://ror.org/012a91z28

  2. 2 Universidad Internacional de Valencia
    info

    Universidad Internacional de Valencia

    Valencia, España

    ROR https://ror.org/00gjj5n39

  3. 3 Ghent University
    info

    Ghent University

    Gante, Bélgica

    ROR https://ror.org/00cv9y106

Revista:
Psicothema

ISSN: 0214-9915

Año de publicación: 2018

Volumen: 30

Número: 2

Páginas: 171-176

Tipo: Artículo

Otras publicaciones en: Psicothema

Resumen

Antecedentes: entender los factores involucrados en la respuesta psicofi siológica ante situaciones de estrés agudo es crucial para prevenir y tratar problemas de salud relacionados con el estrés. El objetivo es integrar los resultados de estudios en humanos relacionados con el papel del sexo y la edad en las diferencias individuales en la respuesta de estrés en diferentes biomarcadores. Metodología: se integran los principales resultados de nuestro grupo de investigación y de otros laboratorios centrados en las diferencias debidas al sexo y la edad en la respuesta psicofi siológica a situaciones de estrés psicosocial. Resultados: se observan diferencias en la respuesta de estrés entre hombres y mujeres en presión sanguínea y en niveles de cortisol, pero no en frecuencia cardíaca, variabilidad de la frecuencia cardíaca y alfa-amilasa. Además, la edad infl uye en los niveles de cortisol y en la actividad basal del sistema nervioso simpático. Conclusiones: los resultados ponen de manifi esto la importancia de tener en cuenta el sexo y la edad de los participantes para poder entender la respuesta de estrés y sus posibles efectos en salud

Información de financiación

This research was supported by the Spanish Education and Science Ministry (SEJ2004-07191/PSIC, SEJ2007-62019/PSIC, PSI2010/21343, PSI2013/46889) and the Generalitat Valenciana (PROMETEO 2011/048 and PROMETEOII2015/20). M.M.P. is a postdoctoral research fellow of the Special Research Fund (BOF; 01P18916) at Gent University.

Financiadores

Referencias bibliográficas

  • Allen, M. T., Bocek, C. M., & Burch, A. E. (2011). Gender differences and the relationships of perceived background stress and psychological distress with cardiovascular responses to laboratory stressors. International Journal of Psychophysiology, 81(3), 209-217. doi:https:// doi.org/10.1016/j.ijpsycho.2011.06.013
  • Allen, M.T., Stoney, C.M., Owens, J.F., & Matthews, K.A. (1993). Hemodynamic adjustments to laboratory stress: The influence of gender and personality. Psychosomatic Medicine, 55(6), 505-517. doi:http://dx.doi.org/10.1097/00006842-199311000-00006
  • Almela, M., Hidalgo, V., van der Meij, L., Pulopulos, M.M., Villada, C., & Salvador, A. (2014). A low cortisol response to acute stress is related to worse basal memory performance in older people. Frontiers in Aging Neuroscience, 6, art 157. doi:10.3389/fnagi.2014.00157
  • Almela, M., Hidalgo, V., Villada, C., van der Meij, L., Espín, L., Gómez-Amor, J., & Salvador, A. (2011). Salivary Alpha-Amylase Response to Acute Psychosocial Stress: The Impact of Age. Biological Psychology, 87(3), 421-429. doi:https://doi.org/10.1016/j. biopsycho.2011.05.008
  • Born, J., Ditschuneit, I., Schreiber, M., Dodt, C., & Fehm, H.L. (1995). Effects of age and gender on pituitary-adrenocortical responsiveness in humans. European Journal of Endocrinology, 132(6), 705-711. doi:10.1530/eje.0.1320705
  • Brindle, R., Ginty, A.T., Phillips, A.C., & Carroll, D. (2014). A tale of two mechanisms: A meta-analytic approach toward understanding the autonomic basis of cardiovascular reactivity to acute psychological stress. Psychophysiology, 51(10), 964-976. doi:10.1111/psyp.12248
  • Buechel, H.M., Popovic, J., Staggs, K.H., Anderson, K.L., Thibault, O., & Blalock, E. (2014). Aged rats are hypo-responsive to acute restraint: Implications for psychosocial stress in aging. Frontier in Aging Neuroscience, 6, 13. doi:10.3389/fnagi.2014.00013
  • Carver, C.S., & Connor-Smith, J. (2010). Personality and coping. Annual Review of Psychology, 61, 679-704. doi:https://doi.org/10.1146/annurev. psych.093008.100352
  • Chida, Y., & Hamer, M. (2008). Chronic psychosocial factors and acute physiological responses to laboratory-induced stress in healthy populations: A quantitative review of 30 years of investigations. Psychological Bulletin, 134(6), 829-885. doi:http://dx.doi.org/10.1037/ a0013342
  • Chrousos, G.P. (2009). Stress and disorders of the stress system. Nature Review Endocrinology, 5(7), 374-381. doi:10.1038/nrendo.2009.106
  • Esler, M.D., Thompson, J.M., Kaye, D.M., Turner, A.G., Jennings, G.L., Cox, H.S., … & Seals, D.R. (1995). Effects of aging on the responsiveness of the human cardiac sympathetic nerves to stressors. Circulation, 91(2), 351-358. doi:https://doi.org/10.1161/01.CIR.91.2.351
  • Espin, L., Almela., M., Hidalgo, V., Villada, C., Salvador, A., & Gómez-Amor, J. (2013). Acute pre-learning stress and declarative memory: Impact of sex, cortisol response and menstrual cycle phase. Hormones and Behavior, 63, 759-765. doi:https://doi.org/10.1016/j. yhbeh.2013.03.013
  • González-Bono, E., Moya-Albiol, L., Salvador, A., Carrillo, E., Ricarte, J., & Gómez-Amor, J. (2002). Anticipatory autonomic response to a public speaking task in women: The role of trait anxiety. Biological Psychology, 60(1), 37-49. doi:https://doi.org/10.1016/S0301-0511(02)00008-X
  • Goodman, W.K., Janson, J., & Wolf, J.M. (2017). Meta-analytical assessment of the effects of protocol variations on cortisol responses to the Trier Social Stress Test. Psychoneuroendocrinology, 80, 26-35. doi:http://dx.doi.org/10.1016/j.psyneuen.2017.02.030
  • Hidalgo, V., Pulopulos, M.M., Puig-Pérez, S., Espin, L., Gómez-Amor, J., & Salvador, A. (2015). Acute stress affects free recall and recognition of pictures differently depending on age and sex. Behavioral Brain Research, 292, 393-402. doi:https://doi.org/10.1016/j.bbr.2015.07.011
  • Hidalgo, V., Villada, C., Almela, M., Espin, L., Gómez-Amor, J., & Salvador, A. (2012). Enhancing effects of acute psychosocial stress on priming of non-declarative memory in healthy young adults. Stress, 15, 329-338. doi:http://dx.doi.org/10.3109/10253890.2011.624224
  • Jacobson, L. (2005). Hypothalamic-pituitary-adrenocortical axis regulation. Endocrinology and Metabolism Clinincs of North America, 34, 271-292, vii.doi:http://dx.doi.org/10.1016/j.ecl.2005.01.003
  • Kajantie, E., & Phillips, D.I.W. (2006). The effects of sex and hormonal status on the physiological response to acute psychosocial stress. Psychoneuroendocrinology, 31(2), 151-178. doi:https://doi. org/10.1016/j.psyneuen.2005.07.002
  • Kelly, M. M., Tyrka, A. R., Anderson, G. M., Price, L. H., & Carpenter, L. L. (2008). Sex differences in emotional and physiological responses to the Trier Social Stress Test. Journal of Behavior Therapy and Experimental Psychiatry, 39(1), 87-98. doi:https://doi.org/10.1016/j. jbtep.2007.02.003
  • Kirschbaum, C., Pirke, K., & Hellhammer, D.H. (1993). The “trier social stress test”: A tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology, 28(1-2), 76-81. doi:https:// doi.org/10.1159/000119004
  • Kudielka, B.M., Buske-Kirschbaum, A., Hellhammer, D.H., & Kirschbaum, C. (2004). HPA axis responses to laboratory psychosocial stress in healthy elderly adults, younger adults, and children: Impact of age and gender. Psychoneuroendocrinology, 29, 83-98. doi:https://doi. org/10.1016/S0306-4530(02)00146-4
  • Kudielka, B.M., Hellhammer, D.H., & Wust, S. (2009). Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge. Psychoneuroendocrinology, 34(1), 2-18. doi:https://doi.org/10.1016/j.psyneuen.2008.10.004
  • Kudielka, B.M., & Kirschbaum, C. (2005). Sex differences in HPA axis responses to stress: A review. Biological Psychology, 69(1), 113-132. doi:http://dx.doi.org/10.1016/j.biopsycho.2004.11.009
  • Kudielka, B.M., Schmidt-Reinwald, A.K., Hellhammer, D.H., Schurmeyer, T., & Kirschbaum, C. (2000). Psychosocial stress and HPA functioning: No evidence for a reduced resilience in healthy elderly men. Stress, 3(3), 229-240. doi:http://dx.doi.org/10.3109/10253890009001127
  • Luisi, S., Tonetti, A., Bernardi, F., Casarosa, E., Florio, P., … & Genazzani, A.R. (1998). Effect of acute corticotropin releasing factor on pituitaryadrenocortical responsiveness in elderly women and men. Journal of Endocrinological Investigation, 21(7), 449-453. doi:10.1007/ BF03347325
  • McEwen, B.S. (2015). Biomarkers for assessing population and individual health and disease related to stress and adaptation. Metabolism, 64(3), S2-S10.DOI:https://doi.org/10.1016/j.metabol.2014.10.029
  • Mizoguchi, K., Ikeda, R., Shoji, H., Tanaka, Y., Maruyama, W., & Tabira, T. (2009). Aging attenuates glucocorticoid negative feedback in rat brain. Neuroscience, 159, 259-270. doi:https://doi.org/10.1016/j. neuroscience.2008.12.020
  • Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., ... & Huffman, M. D. (2015). Executive summary. Circulation, 131(4), 434-441. doi:https://doi.org/10.1161/ CIR.0000000000000157
  • Nichols, N.R., Zieba, M., & Bye, N. (2001). Do glucocorticoids contribute to brain aging? Brain Research Review, 37, 273-286. doi:https://doi. org/10.1016/S0165-0173(01)00131-X
  • Pascualy, M., Petrie, E.C., Brodkin, K., Peskind, E.R., Veith, R.C., & Raskind, M.A. (1999). Effects of advanced aging on plasma catecholamine responses to the cold pressor test. Neurobiology of Aging, 20(6), 637-642. doi:https://doi.org/10.1016/S0197-4580(99)00036-6
  • Puig-Pérez, S., Hackett, R. A., Salvador, A., & Steptoe, A. (2017). Optimism moderates psychophysiological responses to stress in older people with Type 2 diabetes. Psychophysiology, 54, 536-543. doi:10.1111/psyp.12806
  • Puig-Pérez, S., Villada, C., Pulopulos, M.M., Almela, M., Hidalgo, V., & Salvador, A. (2015). Optimism and pessimism are related to different components of the stress response in healthy older people. International Journal of Psychophysiology, 98(2), 213-221. doi:https:// doi.org/10.1016/j.ijpsycho.2015.09.002
  • Puig-Pérez, S., Villada, C., Pulopulos, M.M., Hidalgo, V., & Salvador, A. (2016). How are neuroticism and depression related to the psychophysiological stress response to acute stress in healthy older people? Physiology and Behavior, 156, 128-136. doi:https://doi. org/10.1016/j.physbeh.2016.01.015
  • Pulopulos, M.M., Almela, M., Hidalgo, V., Villada, C., Puig-Pérez, S., & Salvador, A. (2013). Acute stress does not impair long-term memory retrieval in older people. Neurobiology of Learning and Memory, 104, 16-24. doi:https://doi.org/10.1016/j.nlm.2013.04.010
  • Pulopulos, M.M., Hidalgo, V., Almela, M., Puig-Pérez, S., Villada, C., & Salvador, A. (2015). Acute stress and working memory in older people. Stress, 18(2), 178-187. doi:http://dx.doi.org/10.3109/10253890.2015.10 04538
  • Pulopulos, M.M., Hidalgo, V., Puig-Pérez, S., & Salvador, A. (2016) Cortisol awakening response and cognitive performance in hypertensive and normotensive older people. Hormones and Behavior, 83, 75-82. doi:https://doi.org/10.1016/j.yhbeh.2016.05.014
  • Rohleder, N., Kudielka, B.M., Hellhammer, D.H., Wolf, J.M., & Kirschbaum, C. (2002). Age and sex steroid-related changes in glucocorticoid sensitivity of pro-infl ammatory cytokine production after psychosocial stress. Journal of Neuroimmunology, 126(1-2), 6977. doi:https://doi.org/10.1016/S0165-5728(02)00062-0
  • Rohleder, N., & Nater, U.M. (2009). Determinants of salivary alpha-amylase in humans and methodological considerations. Psychoneuroendocrinology, 34, 469-485. doi:https://doi.org/10.1016/j.psyneuen.2008.12.004
  • Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2001). How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocrine Review, 21, 55-89. doi:https://doi.org/10.1210/edrv.21.1.0389
  • Seals, D.R., & Dinenno, F.A. (2004). Collateral damage: cardiovascular consequences of chronic sympathetic activation with human aging. American Journal of Physiology: Heart and Circulatory Physiology, 287(5), H1895-H1905. doi:10.1152/ajpheart.00486.2004
  • Steptoe, A., Dockray, S., & Wardle, J. (2009). Positive affect and psychobiological processes relevant to health. Journal of Personality, 77(6), 1747-1776. doi:10.1111/j.1467-6494.2009.00599.x
  • Strahler, J., Mueller, A., Rosenloecher, F., Kirschbaum, C., & Rohleder, N. (2010). Salivary alpha-amylase stress reactivity across different age groups. Psychophysiology, 47(3), 587-595. doi:10.1111/j.14698986.2009.00957.x
  • Strahler, J., Skoluda, N., Kappert, M. B., & Nater, U. M. (2017). Simultaneous measurement of salivary cortisol and alpha-amylase: Application and recommendations. Neuroscience & Biobehavioral Review, 83, 657677. doi:https://doi.org/10.1016/j.neubiorev.2017.08.015
  • Traustadóttir, T., Bosch, P.R., & Matt, K.S. (2005). The HPA axis response to stress in women: Effects of aging and fi tness. Psychoneuroendocrinology, 30(4), 392-402. doi:https://doi. org/10.1016/j.psyneuen.2004.11.002
  • Uchino, B.N., Uno, D., Holt-Lunstad, J., & Flinders, J.B. (1999). Age-related differences in cardiovascular reactivity during acute psychological stress in men and women. Journal of Gerontology Series B: Psychological Science Social Science, 54(6), 339-346. doi:https:// doi.org/10.1093/geronb/54B.6.P339
  • Ulrich-Lai, Y.M., & Herman, J.P. (2009). Neural regulation of endocrine and autonomic stress responses. Nature Review Neuroscience, 10(6), 397-409. doi:10.1038/nrn2647
  • Villada, C., Espin, L., Hidalgo, V., Rubagotti, S., Sgoifo, A., & Salvador, A. (2017). The influence of coping strategies and behavior on the physiological response to social stress in women: The role of age and menstrual cycle phase. Physiology & Behavior, 170, 37-46. doi:https:// doi.org/10.1016/j.physbeh.2016.12.011
  • Wood, R., Maraj, B., Lee, C.M., & Reyes, R. (2002). Short-term heart rate variability during a cognitive challenge in young and older adults. Age and Ageing, 31(2), 131-135. doi:https://doi.org/10.1093/ ageing/31.2.131
  • Zandara, M., García-Lluch, M., Pulopulos, M.M., Hidalgo, V., Villada, C., & Salvador, A. (2016). Acute stress and working memory: The role of sex and cognitive stress appraisal. Physiology and Behavior, 164 (Part A), 336-344. doi:https://doi.org/10.1016/j.physbeh.2016.06.022