Oral rehabilitation with dental implants in patients with recessive dystrophic epidermolysis bullosaa retrospective study with 2-15 years of follow-up

  1. David Peñarrocha Oltra 1
  2. Rubén Agustín Panadero 2
  3. Blanca Serra Pastor 3
  4. María Peñarrocha Diago 4
  5. Miguel Peñarrocha Diago 5
  1. 1 DDS, PhD. Adjunct Lecturer, Unit of Oral Surgery, Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain
  2. 2 DDS, PhD. Adjunct Lecturer, Unit of Prosthodontics and Occlusion, Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain
  3. 3 DDS. Associate Professor, Unit of Prosthodontics and Occlusion, Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain
  4. 4 MD, DDS, PhD. Full Professor, Unit of Oral Surgery, Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain
  5. 5 MD, DDS, PhD. Chairman of Oral Surgery, Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain
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Revista:
Medicina oral, patología oral y cirugía bucal. Ed. inglesa

ISSN: 1698-6946

Año de publicación: 2020

Volumen: 25

Número: 2

Páginas: 14

Tipo: Artículo

DOI: 10.4317/MEDORAL.23331 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Medicina oral, patología oral y cirugía bucal. Ed. inglesa

Objetivos de desarrollo sostenible

Resumen

Epidermolysis bullosa (EB) comprises a group of hereditary disorders characterized by mechanical fragility of the skin and mucous membranes, with the development of blisters and vesicles in response to minimum tissue friction. Recessive dystrophic epidermolysis bullosa (RDEB) with generalized involvement is the most common subtype in the oral cavity. The present study was carried out to investigate dental implant survival, peri-implant tissue condition, patient satisfaction, and the impact of treatment upon the quality of life of patients with RDEB rehabilitated with implants and full-arch implant-supported prostheses. Thirteen patients with RDEB underwent dental implant treatment between September 2005 and December 2016. A retrospective study was made to analyze implant survival, peri-implant tissue health and patient satisfaction. A total of 80 implants were placed (42 in the maxilla and 38 in the mandible) in 13 patients between 20-52 years of age and diagnosed with RDEB. All the implants were rehabilitated on a deferred basis with 20 full-arch prostheses. Fifteen fixed prostheses and 5 implant-supported overdentures were placed. The implant survival rate was 97.5% after a mean follow-up of 7.5 years after prosthetic loading. Fifty percent of the implants showed mucositis at the time of evaluation. Probing depth was maintained at 1-3 mm in 96.2% of the implants, and bleeding upon probing was observed in 67.5% of the implants. There was a high prevalence of bacterial plaque (85%). The treatment of edentulous patients with RDEB by means of implants and implant-supported prostheses is predictable as evidenced by the high success rate, and improves patient self-esteem and quality of life.

Referencias bibliográficas

  • Fine, JD,Bruckner-Tuderman, L,Eady, RA,Bauer, EA,Bauer, JW,Has, C. (2014). Inherited epidermolysis bullosa: updated recommendations on diagnosis and classification. J Am Acad Dermatol. 70. 1103
  • Krämer, SM,Serrano, MC,Zillmann, G,Gálvez, P,Araya, I,Yanine, N. (2012). Oral health care for patients with epidermolysis bullosa--best clinical practice guidelines. Int J Paediatr Dent. 22. 1-35
  • Wright, JT. (2010). Oral manifestations in the epidermolysis bullosa spectrum. Dermatol Clin. 28. 159
  • Feijoo, JF,Bugallo, J,Limeres, J,Peñarrocha, D,Peñarrocha, M,Diz, P. (2011). Inherited epidermolysis bullosa:an update and suggested dental care considerations. J Am Dent Assoc. 142. 1017
  • Reichart, PA,Schmidt-Westhausen, AM,Khongkhunthian, P,Strietzel, FP. (2016). Dental implants in patients with oral mucosal diseases - a systematic review. J Oral Rehabil. 43. 388
  • Candel-Marti, ME,Ata-Ali, J,Peñarrocha-Oltra, D,Peñarrocha-Diago, M,Bagán, JV. (2011). Dental implants in patients with oral mucosal alterations: An update. Med Oral Patol Oral Cir Bucal. 16. 787
  • Peñarrocha-Diago, M,Serrano, C,Sanchis, JM,Silvestre, FJ,Bagán, JV. (2000). Placement of endosseous implants in patients with oral epidermolysis bullosa. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 90. 587
  • Diz, P,Scully, C,Sanz, M. (2013). Dental implants in the medically compromised patient. J Dent. 41. 195-206
  • Agustín-Panadero, R,Gomar-Vercher, S,Peñarrocha-Oltra, D,Guzmán-Letelier, M,Peñarrocha-Diago, M. (2015). Fixed full-arch implant-supported prostheses in a patient with epidermolysis bullosa: a clinical case history report. Int J Prosthodont. 28. 33
  • Peñarrocha-Oltra, D,Aloy-Prósper, A,Ata-Ali, J,Peñarrocha-Diago, M,Peñarrocha-Diago, M. (2012). Implants placed simultaneously with particulated bone graft in patients diagnosed with recessive dystrophic epidermolysis bullosa. J Oral Maxillofac Surg. 70. 51
  • Finke, C,Haas, N,Czarnetzki, BM. (1996). [Value of dental treatment in interdisciplinary management of a child with epidermolysis bullosa dystrophica hereditaria (Hallopeau-Siemens)]. Hautarzt. 47. 307
  • Azrak, B,Kaevel, K,Hofmann, L,Gleissner, C,Willershausen, B. (2006). Dystrophic epidermolysis bullosa: oral findings and problems. Spec Care Dentist. 26. 111
  • Wright, JT,Fine, JD,Johnson, L. (1993). Hereditary epidermolysis bullosa: oral manifestations and dental management. Pediatr Dent. 15. 242
  • Peñarrocha, M,Larrazábal, C,Balaguer, J,Serrano, C,Silvestre, J,Bagán, JV. (2007). Restoration with implants in patients with recessive dystrophic epidermolysis bullosa and patient satisfaction with the implant-supported superstructure. Int J Oral Maxillofac Implants. 22. 651
  • Penarrocha, M,Rambla, J,Balaguer, J,Serrano, C,Silvestre, J,Bagán, JV. (2007). Complete fixed prostheses over implants in patients with oral epidermolysis bullosa. J Oral Maxillofac Surg. 65. 103
  • Peñarrocha-Oltra, D,Peñarrocha-Diago, M,Balaguer-Martínez, J,Ata-Ali, J,Peñarrocha-Diago, M. (2011). Full-arch fixed prosthesis supported by four implants in patients with recessive dystrophic epidermolysis bullosa. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 112. 4-10
  • Renvert, S,Persson, GR,Pirih, FQ,Camargo, PM. (2018). Peri-implant health, peri-implant mucositis, and peri-implantitis: Case definitions and diagnostic considerations. J Clin Periodontol. 20. 278
  • Pellicer-Chover, H1,Peñarrocha-Diago, M,Peñarrocha-Oltra, D,Gomar-Vercher, S,Agustín-Panadero, R,Peñarrocha-Diago, M. (2016). Impact of crestal and subcrestal implant placement in peri-implant bone: A prospectivecomparative study. Med Oral Patol Oral Cir Bucal. 21. 103
  • Agustín-Panadero, R,Serra-Pastor, B,Peñarrocha-Oltra, D,Peñarrocha-Diago, M. (2017). Maxillary Implant Prosthodontic Treatment Using Digital Laboratory Protocol for a Patient with Epidermolysis Bullosa: A Case History Report. Int J Prosthodont. 30. 390
Fuente de los datos: Dialnet