Sordera súbita idiopáticarevisión de 58 casos

  1. Jonathan DELGADO-GIL 1
  2. Claudio KRSTULOVIC
  3. Vanesa PÉREZ-GUILLÉN
  4. Enrique GARCÍA ZAMORA 1
  5. Herminio PÉREZ GARRIGUES
  1. 1 Hospital La Fe. Valencia
Journal:
Revista ORL

ISSN: 2444-7986 2444-7986

Year of publication: 2019

Volume: 10

Volume: 4

Pages: 235-243

Type: Article

DOI: 10.14201/ORL.20151 DIALNET GOOGLE SCHOLAR lock_openDialnet editor

More publications in: Revista ORL

Abstract

Objective: Sudden deafness is defined as sudden-onset sensorineural hearing loss in less than 72 hours, with loss of 30 or more decibels (dB) at three consecutive frequencies in tonal audiometry. In 90% of the cases it is not possible to determine its etiology giving rise to what is known as idiopathic sudden deafness. Our objective is To describe patient’s characteristics with diagnosed ISHL in the last twenty years, to identify prognostic factors and show the results in regards of treatment. Method: Retrospective descriptive study of 58 patients, diagnosed with ISHL between 1995-2016. Level of hearing loss was determined as well as the degree of posterior recovery. Cardiovascular risk factors were studied, in addition to association with other symptoms, the onset of treatment, severity of hearing loss and morphology of the audiometric curve. Results: No association was found between hearing recovery and different cardiovascular risk factors. 24.1% of the patients presented a complete improvement. Partial improvement and mild improvement were obtained in 17.2% each. 41.5% did not obtain any improvement with a worse hearing prognosis in those patients with profound hearing loss. 100% of recovery was obtained in subjects with ascending audiometric morphology. The most common associated symptom was tinnitus. Accompanying vestibular symptoms as an initial manifestation determine a worse hearing prognosis. Starting time from the emergence of hypoacusis until the instauration of systemic (IV) treatment was not related to a better prognosis. 54% of the patients did not show any improvements with ITD and systemic treatment compared to a 75% in those treated exclusively with systemic treatment. This was not statistically significant. Conclusions: Vestibular involvement, hypoacusis severity and hearing curve morphology are determinant prognostic factors. Although there are good outcomes published using ITD as recovery treatment, our experience does not determine an evident benefit of its use on subjects with ISHL.

Bibliographic References

  • 1. Schreiber BE, Agrup C, Haskard DO, Luxon LM. Sudden sensorineural hearing loss. Lancet. 2010; 375:1203-11.
  • 2. Stachler RJ, Chandrasekhar SS, Archer SM, Rosenfeld RM, Schwartz SR, Barrs DM, et al. Clinical practice guideline: sudden hearing loss. Otolaryngol Head Neck Surg. 2012. 146(3 Suppl):S1–S35.
  • 3. Xenellis J, Karapatsas I, Papadimitriou N, Nikolopoulos T,Maragoudakis P, Tzagkaroulakis M, et al. Idiopathic sudden sen-sorineural hearing loss: prognostic factors. J Laringol otol. 2006;120:718-24.
  • 4. Byl FM. Sudden hearing loss: eight years experience and suggested prognostic table. Laryngoscope. 1984; 94: 647-61.
  • 5. Teranishi M, Katayama N, Uchida Y, Tominaga M, Nakashima T. Thirty-year trends in sudden deafness from four nationwide epidemiological surveys in Japan. Acta Otolaryngol.2007;127: 1259-65.
  • 6. Siegel LG. The treatment of idiopathic sudden sensorineural hearing loss. Otolaryngol Clin North Am.1975; 8:467-73.
  • 7. Mamak A, Yilmaz S, Cansiz H, Inci E, Güçlü E, Dereköylü L. A study of prognostic factors in sudden hearing loss. Ear Nose Throat J. 2005; 84: 641-44.
  • 8. Cvorovic L, Deric D, Probst R, Hegemann S. Prognostic model for predicting hearing recovery in idiopathic sudden sensorineural hearing loss. Otol Neurotol. 2008; 29:4649.
  • 9. Narozny W, Kuczkowski J, Kot J, Stankiewicz C, Sicko Z,Mikaszewski B. Prognostic factor in sudden sensorineural hearing loss: our experience and a review of the literature. Ann Otol Rhinol Laryngol. 2006;115:553-8.
  • 10. Chang NC, Kuen-Yao Ho MD, Kuo WR. Audiometric patterns prognosis in sudden sensorineural hearing loss in Southern Taiwan. Otolaryngol Head Neck Surg. 2005;133:916-22.
  • 11. Shaia FT, Sheehy JL. Sudden sensorineural hearing impairment. A report of 1220 cases. Laryngoscope. 1976; 86: 389-98.
  • 12. Nosrati-Zarenoe R, Arlinger S, Hultcrantz E. Idiopathic sudden sensorineural hearing loss: results drawn from the Swedish national database. Acta Otolaryngol. 2007;127:1168-75.
  • 13. Samim E, Kilic R, Ozdek A, Gocman H, Eryilmaz A, UnluI. Combined treatment of sudden sensorineural hearing loss with steroid, dextran and piracetam: experience with 68 cases. Eur Arch Otorhinolaryngol. 2004; 261:187-90.
  • 14. Marcucci R, AlessandrelloLiotta A, Cellai AP, Rogolino A, Berloco P, Leprini E, et al. Cardiovascular and thrombophilic risk factors for idiopathic sudden sensorineural hearing loss. J Thromb Haemost. 2005; 3:929-34.
  • 15. Lin HC, Chao PZ, Lee HC. Sudden sensorineural hearing los increases the risk of stroke: a 5-year follow-up study. Stroke. 2008; 39:2744-8.
  • 16. Capaccio P, Cuccarini V, Ottaviani F, et al. Prothrombotic gene mutations in patients with sudden sensorineural hearing loss and cardiovascular thrombotic disease. Ann Oto Rhino Laryngol. 2009; 118:205-10.
  • 17. Chau JK, Lin JR, Atashband S, Irvine RA, Westerberg BD. Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss. Laryngoscope. 2010; 120: 1011-21.
  • 18. Capaccio P, Ottaviani F, Cuccarini V, Bottero A, Schindler A, Cesana B, et al. Genetic and acquired prothrombotic risk factors and sudden hearing loss. Laryngoscope. 2007; 117: 547-551.
  • 19. Ballesteros F, Alobid I, Tassies D, Reverter JC, Scharf R E, Guilemany JM, et al. Is there an overlap between sudden neurosensorial hearing loss and cardiovascular risk factors? Audiol Neurotol. 2009; 14(3): 139-145.
  • 20. Cadoni G, Agostino S, Scipione S, Ippolito S, Caselli A, Marchese R, Et al. Sudden sensorineural hearing loss: Our experience in diagnosis, treatment, and outcome. J Otolaryngol. 2005; 34, 395-401.
  • 21. Mattox DE, Simmons FB. Natural history of sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol. 1977;86:463-80.
  • 22. Ceylan A, Celenk F, Kemaloglu YK, Bayazit YA, Goksu N, OzbilenS. Impact of prognostic factors on recovery from sudden hearing loss. J Laryngol Otol. 2007;121:1035-40.
  • 23. Weber PC, Zbar RI, Gantz BJ. Appropriateness of magnetic resonance imaging in sudden sensorineural hearing loss. Otolaryngol Head Neck Surg. 1997,116:153-6.
  • 24. Huy PT, Sauvaget E. Idiopathic sudden sensorineural hearing loss is not an otologic emergency. Otol Neurotol. 2005; 26: 896-902.
  • 25. Zadeh MH, Storper IS, Spitzer JB. Diagnosis and treatment of sudden-onset sensorineural hearing loss: A study of 51 patients. Otolaryngol Head Neck Surg. 2003; 128: 92-98.
  • 26. Fujimoto C, Egami N, Kinoshita M, Sugasawa K, Yamasoba T, Iwasaki S. Involvement of vestibular organs in idiopathic sudden hearing loss with vertigo: an analysis using oVEMP and cVEMP testing. Clin Neurophysiol.2015; 126(5):1033-8.
  • 27. Sakata T, Kato T. Feeling of ear fullness in acute sensorineural hearing loss. Acta Otolaryngol. 2006; 126: 828-33.
  • 28. Furuhashi A, Mastuda K, Asahi K, Nakashima T. Sudden deafness: long-term follow-up and recurrence. Clin Otolaryngol. 2002; 27:458-63.
  • 29. Guyot JP, Thielen K. Evolution of sudden deafness without treatment. Schweiz Med Wochenschr. 2000; 116: 93-96.
  • 30. Rauch SD. Clinica lpractice. Idiopathic sudden sensorineural hearing loss. N Engl J Med. 2008; 359:833-40.
  • 31. Stokroos RJ, Albers FW, Tenvergert EM. Antiviral treatment of idiopathic sudden sensorineural hearing loss: a prospective, randomized, doubleblind clinical trial. Acta Otolaryngol.1998; 118:488-95.
  • 32. Tucci DL, Farmer Jr JC, Kitch RD, Witsell DL. Treatment of sudden sensorineural hearing loss with systemic steroids and valacyclovir. Otol Neurotol. 2002; 23:301-8.
  • 33. Bennett M, Kertesz T, Yeung P. Hyperbaric oxygen therapy for idiopathic sudden sensorineural hearing loss and tinnitus: a systematic review of randomized controlled trials. J Laryngol Otol. 2005; 119:791-8.
  • 34. Wilson W, Byl F, Laird N. The efficacy of steroids in the treatment of idio-pathic sudden hearing loss a double-blind clinical study. Arch Otolaryngol.1980; 106:772-6.
  • 35. Wei B, Mubiru S, O’Leary S. Steroids for idiopathic sudden sensorineural hearing loss. Cochrane Database of Systematic Reviews 2006, Issue 1. Art. No: CD003998. DOI: 10.1002/14651858. CD003998.pub2.
  • 36. Marx M, Younes E, Chandrasekhar SS, Ito J, Plontke S, O’Leary S, Et al. International consensus (ICON) on treatment of sudden sensorineural hearing loss. Eur Ann Otorhinolaryngol Head Neck Dis. 2018; 135(1S):S23-S28.
  • 37. Bird PA, Begg EJ, Zhang M, Keast AT, Murray DP, Balkany TJ. Intratympanic versus intravenous delivery of methylprednisoloneto cochlear perilymph. Otol Neurotol. 2007; 28:1124-30.
  • 38. Kosyakov S, Atanesyan A, Gunenkov A, Ashkhatunyan E, Kurlova A. Intratympanic steroids for sudden sensorineura lhearing loss. Int Adv Otol. 2011; 7:323-32.
  • 39. Ho Guan-Min, MD, PhD; Lin Hung-Ching, MD; Shu Min-Tsan, MD; Yang Cheng-Chien, MD; Tsai Hsun-Tien, MD, PhD. Effectiveness of Intratympanic Dexamethasone Injection in SuddenDeafness Patients as Salvage Treatment. Laryngoscope. 2004; 114:1184-89.
  • 40. Battaglia A, Burchette R, Cueva R. Combination Therapy (Intratympanic Dexamethasone + HighDose Prednisone Taper) for the Treatment of Idiopathic Sudden sensorineural Hearing Loss. Otol Neurotol. 2008; 29:453-60.
  • 41. Joong HA, Myung HY, Tae HY, Jong WC. Can Intratympanic Dexamethasone Added to Systemic Steroids Improve Hearing Outcome in Patients With Sudden Deafness? Laryngoscope. 2008; 118:279-82.