Epstein-Barr virus in oral proliferative verrucous leukoplakia and squamous cell carcinomaa preliminary study

  1. José Vicente Bagán Sebastián 1
  2. Yolanda Jiménez Soriano 1
  3. Judith Murillo Cortés 1
  4. Rafael Poveda Roda 1
  5. José María Díaz Fernández 1
  6. Carmen Gavaldá Esteve 1
  7. María Margaix Muñoz 1
  8. Crispian Scully 2
  9. Trinidad M. Alberola
  10. Manuela Torres Puente
  11. Manuel Pérez Alonso 3
  1. 1 University General Hospital, Valencia
  2. 2 University College London, London, UK
  3. 3 Universitat de València
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    Universitat de València

    Valencia, España

    ROR https://ror.org/043nxc105

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Revista:
Medicina oral, patología oral y cirugía bucal. Ed. inglesa

ISSN: 1698-6946

Año de publicación: 2008

Volumen: 13

Número: 2

Páginas: 5

Tipo: Artículo

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Otras publicaciones en: Medicina oral, patología oral y cirugía bucal. Ed. inglesa

Resumen

The aim of this study was to analyze proliferative verrucous leukoplakia (PVL) and oral squamous cell carcinoma (OSCC) for the possible presence of Epstein-Barr virus (EBV). We studied three groups: Sub-Group 1 was composed of 10 patients with PVL, (6 of whom had developed OSCC); Sub-Group 2 comprised 5 patients with OSCC but no preceding PVL; and Sub-Group 3 were 5 controls with clinically normal oral mucosa. Oral biopsies from all cases were examined for Epstein-Barr virus (EBV) by nested PCR. EBV was detected in 60% of Sub-Group 1 patients (PVL ) and in 40% of Sub-Group 2 (OSCC), but in 0% of SubGroup 3 (controls).

Fuente de los datos: Dialnet