Negative affect, perceived health, and endocrine and immunological levels in caregivers of offspring with schizophrenia

  1. Sara De Andrés-García 1
  2. Irene Cano-López 1
  3. Luis Moya-Albiol 1
  4. Esperanza González-Bono 1
  1. 1 Universitat de València (España)
Revista:
Psicothema

ISSN: 0214-9915

Año de publicación: 2016

Volumen: 28

Número: 4

Páginas: 377-382

Tipo: Artículo

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Otras publicaciones en: Psicothema

Resumen

Antecedentes: afecto negativo (AN) y estrés crónico se asocian con desequilibrios de salud, y la interacción entre ambos permanece desconocida. El cuidado de familiares a largo plazo es un modelo de estudio, ya que informan de estrés crónico y problemas de salud. El objetivo es examinar el papel del AN sobre la respuesta de estrés y la salud en cuidadores de esquizofrenia. Método: cuarenta-y-un cuidadores fueron distribuidos en dos grupos de acuerdo con su AN y trece no cuidadores formaron el grupo control. Los participantes fueron expuestos a un estresor psicosocial agudo repetido, midiéndose el cortisol, la inmunoglobulina A (IgA) y el nivel de conductancia cutánea (SCL) antes, durante y después del estrés. También se evaluó el estado de ánimo, el estado de ansiedad, las condiciones de cuidado y la salud percibida. Resultados: los cuidadores con mayor AN muestran peor salud, y mayores disminuciones de cortisol y de respuesta de IgA que los cuidadores con menor AN y los no cuidadores. Conclusiones: el AN podría reducir la capacidad para desarrollar respuestas psicofisiológicas adaptativas al estrés. Desde un punto de vista preventivo, la evaluación de AN podría ser útil para la detección precoz en poblaciones de alto riesgo.

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Información de financiación

This research was supported by the Generalitat Valenciana (grant no. GV06/382 and grant no. PROMETEOII/2015/020) and the University of Valencia (UV-INV-AE15-349947). Irene Cano- L?pez was supported by the FPU Program of the Spanish Ministry of Education, Culture and Sport (grant number FPU14/00471).

Financiadores

Referencias bibliográficas

  • Aguilera, G. (2011). HPA axis responsiveness to stress: Implications for healthy aging. Experimental Gerontology, 46, 90-95.
  • Benson, P. R., & Karlof, K. L. (2009). Anger, stress proliferation, and depressed mood among parents of children with ASD: A longitudinal replication. Journal of Autism and Developmental Disorders, 39, 350- 362.
  • Bobes, J., Portilla, M. P., Bascaran, M. T., Saiz, P. A., & Bousoño, M. (2002). Escala de evaluación de la actividad global [Global Activity Evaluation Scale]. Banco de instrumentos básicos para la práctica de psiquiatría clínica. Madrid, España: Psiquiatría.
  • Carver, C. S., Scheier, M. F., & Weintraub, J. K. (1989). Assessing coping strategies: A theoretically based approach. Journal of Personality and Social Psychology, 56, 267-283.
  • Chang, H., Chiou, C., & Chen, N. (2010). Impact of mental health and caregiver burden on family caregivers’ physical health. Archives of Gerontology and Geriatrics, 50, 267-271.
  • Cooper, C., Katona, C., Orrell, M., & Livingston, G. (2008). Coping strategies, anxiety and depression in caregivers of people with Alzheimer’s disease. International Journal of Geriatric Psychiatry, 23, 929-936.
  • De Andrés-García, S., Moya-Albiol, L., & González-Bono, E. (2012). Salivary cortisol and immunoglobulin A responses to stress as predictors of health complaints reported by caregivers of offspring with Autistic Spectrum Disorder. Hormones and Behavior, 62, 464-474.
  • Denollet, J., & Pedersen, S. S. (2009). Anger, depression and anxiety in cardiac patients: The complexity of individual differences in psychological risk. Journal of American College of Cardiology, 53, 947-949.
  • DeSteno, D., Gross, J. J., & Kubzansky, L. (2013). Affective science and health: The importance of emotion and emotion regulation. Health Psychology, 32, 474-486.
  • Epel, E. S., Lin, J., Dhabhar, F. S., Wolkowitz, O. M., Puterman, E., Karan, L., & Blackburn, E. H. (2010). Dynamics of telomerase activity in response to acute psychological stress. Brain, Behavior, and Immunity, 24, 531-539.
  • Goldberg, D. P., & Hillier, V. (1979). A scaled version of the general health questionnaire. Psychological Medicine, 9, 139-145.
  • González-Bono, E., De Andrés-García, S., & Moya-Albiol, L. (2011). The cortisol awakening response in caregivers of schizophrenic offspring shows sensitivity to patient status. Anxiety Stress Coping, 24, 107-120.
  • Hajcak, G., McDonald, N., & Simons, R. F. (2004). Error-related psychophysiology and negative affect. Brain and Cognition, 56, 189-197.
  • Kirschbaum, C., Pirke, K. M., & Hellhammer, D. H. (1993). The ‘Trier social stress Test’- a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology, 28, 76-81.
  • Laidlaw, T. M., Coverdale, J. H., Falloon, I. R. H., & Kydd, R. R. (2002). Caregivers’ stresses when living together or apart from patients with chronic schizophrenia. Community Mental Health Journal, 38, 303- 310.
  • Levenson, R. W. (1992). Autonomic nervous system patterning in emotion. Psychological Science, 3, 23-27.
  • Lovell, B., Moss, M., & Wetherell, M. (2012a). The psychosocial, endocrine and immune consequences of caring for a child with autism or ADHD. Psychoneuroendocrinology, 37, 534-542.
  • Lovell, B., Moss, M., & Wehterell, M. (2012b). With a little help from my friends: Psychological, endocrine and health corollaries of social support in parental caregivers of children with autism or ADHD. Research in Developmental Disabilities, 33, 682-687.
  • Marsland, A. L., Cohen, S., Rabin, B. S., & Manuck, S. B. (2001). Associations between stress, trait negative affect, acute immune reactivity, and antibody response to hepatitis B injection in healthy young adults. Health Psychology, 20, 4-11.
  • McEwen, B. S., & Stellar, E. (1993). Stress and the individual. Mechanisms leading to disease. Archives of Internal Medicine, 153, 2093-2101.
  • McNair, D., Lorr, M., & Droppleman, L. (1992). POMS manual: Profile of mood states. San Diego, CA: Educational and Industrial Testing Service.
  • Möller-Leimkühler, A. M., & Mädger, F. (2011). Personality factors and mental health outcome in caregivers of first hospitalized schizophrenic and depressed patients: 2-years follow-up results. European Archives of Psychiatry and Clinical Neuroscience, 261, 165-172.
  • Nesic, J., & Duka, T. (2006). Gender specific effects of a mild stressor on alcohol cue reactivity in heavy social drinkers. Pharmacology, Biochemistry and Behavior, 83, 239-248.
  • Peralta, V., & Cuesta, M. J. (1994). Psychometric properties of the Positive and Negative Syndrome Scale (PANSS) in schizophrenia. Psychiatry Research, 53, 31-40.
  • Quirin, M., Kazén, M., Rohrmann, S., & Kuhl, J. (2009). Implicit but not explicit affectivity predicts circadian and reactive cortisol: Using the implicit positive and negative affect test. Journal of Personality, 77, 401-425.
  • Sandín, B., & Chorot, P. (1995). Escala de síntomas somáticos revisada [Scale of Somatic Symptoms (RSSS)]. Madrid, España: Universidad Nacional de Educación a Distancia (UNED).
  • Sherbourne, C. D., & Stewart, A. L. (1991). The MOS social support survey. Social Science and Medicine, 32, 705-712.
  • Spielberger, C. D., Gorsuch, R. L., & Lushene, R. E. (1970). Manual for the State-Trait Anxiety Inventory. Palo Alto, CA: Consulting Psychologists Press.
  • Spielberger, C. D., Jacobs, G., Russell, S., & Crane, R. S. (1983). Assessment of anger: the state-trait anger scale. In C. D. Spielberger & J. N. Butcher (Eds), Advances in personality assessment (pp. 159- 187). Hillsdale, NJ: Lawrence Erlbaum Associates, Inc.
  • Steptoe, A., Wardle, J., & Marmot, M. (2005). Positive affect and health-related neuroendocrine, cardiovascular, and inflammatory processes. Proceedings of the National Academy of Sciences of the United States of America, 108, 6508-6512.
  • Zarit, S. H., Reever, K. E., & Bach-Peterson, J. (1980). Relatives of the impaired elderly: Correlates of feelings of burden. Gerontologist, 20, 649-655.
  • Lovell, B., & Wetherell, M. A. (2011). The cost of caregiving: Endocrine and immune implications in elderly caregivers. Neuroscience & Biobehavioral Reviews, 35, 1342-1352.
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