Valores de normalidad en parámetros oculares en niños caucásicos españoles
- Bueno Gimeno, Inmaculada
- Gené Sampedro, Andrés
- España Gregori, Enrique
ISSN: 1692-8415, 2389-8801
Año de publicación: 2015
Volumen: 13
Número: 1
Páginas: 137-152
Tipo: Artículo
Otras publicaciones en: Ciencia y Tecnología para la Salud Visual y Ocular
Resumen
Objective: To quantify the ocular biometric parameters, the corneal biomechanical properties, the anatomical configuration of the optic nerve and the retinal nerve fiber layer (RNFL) in a group of children through non-invasive techniques. Material and methods: A cross-sectional, descriptive and non-randomized study was conducted in 293 healthy Caucasian children between the ages of 6 and 17. The subjects were divided according to refractive error. Results: A statistically significant correlation was found between axial length (AL) and corneal hysteresis (CH) (p < 0.001). CH decrease was also found with increasing myopia, and CH increase with increasing hypermetropia (p < 0.001). In the posterior segment, a positive correlation was found between the average thickness of the RNFL and the CH (p = 0.01). Likewise, a decrease in the average thickness of the RNFL was observed with the increased AL (p < 0.001) and myopia (p < 0.0001). Conclusions: The mechanical strength of the anterior segment of the eye is affected in myopic subjects at early ages and in severe myopia, regardless of age. Lower CH values, in addition to a reduction in the corneal viscoelastic damping capacity, indicate the existence of a more easily deformable optic nerve, together with a thinning of the RNFL, especially in myopic children. This study provides normal values of these parameters and makes it possible to correlate them with refractive errors.
Referencias bibliográficas
- Referencias Asamblea Médica Mundial (1964). Declaración de Helsinki de la AMM. Principios éticos para las investigaciones médicas en seres humanos. Recuperado de http://www.wma.net/es/30publications/10policies/b3/
- Cantor, L. et al. (2001). Open-angle glaucoma. En Basic and clinical Science course. Glaucoma (pp. 10-72). San Francisco: The Foundation of the American Academy of Ophthalmology.
- Carbonaro, F., Andrew, T., Mackey, D. A., Spector, T. D. y Hammond, C. J. (2008). The heritability of corneal hysteresis and ocular pulse amplitude: a twin study. Ophthalmology, 115, 1545-1549.
- Carkeet, A., Saw, S.-M.., Gazzard, G., Tang, W. y Tan, D. T. (2004). Repeatability of IOL Master Biometry in Children. Optom. Vis. Sci., 81, 829-834.
- Chang, P. y Chang, S. W. (2013). Corneal biomechanics, optic disc morphology and macular ganglion cell complex in myopia. J. Glaucoma, 22(5), 358-362. Doi: 10.1097/IJG.0b013e3182447a17
- Chang, S. W., Tsai, I. L., Hu, F. R., Lin, L. L. y Shih, Y. F. (2001). The cornea in young myopic adults. Br. J. Ophthalmol., 85, 961-970.
- Cho, P. y Lam, C. (1999). Factors affecting the central corneal thickness of Hong Kong Chinese. Curr, Eye Re., 18, 368-374.
- Doughty, M. J. y Zaman, M. L. (2000). Human corneal thickness and its impact on intraocular pressure measures: a review and metaanalysis approach. Surv. Ophthalmol., 44, 367-408.
- Drexler, W., Findl, O., Menapace, R., Rainer, G., Vass, C., Hitzenberger, C. K. y Fercher, A. F. (1998). Partial coherence interferometry: a novel approach to biometry in cataract surgery. Am. J. Ophthalmol., 126, 524-534.
- Ehlers, N., Bramsen, T. y Sperling, S. (1975). Applanation tonometry and central corneal thickness. Acta Ophthalmol., 53, 34-43.
- Fam, H. B., How, A. C., Baskaran, M., Lim, K. Y., Chan, Y. H. y Aung, T. (2006). Central corneal thickness and its relationship to myopia in Chinese adults. Br. J. Ophthalmol., 90, 1451-1453.
- Garner, L. F., Stewart, A. W., Owens, H., Kinnear, R. F. y Frith, M. J. (2006). The Nepal Longitudinal Study: biometric characteristics of developing eyes. Optom. Vis. Sci., 83, 274-280.
- Goss, D. A. y Jackson, T. W. (1992). Ocular dioptric components prior to youth onset of myopia. Optom. Vis. Sci., 69, 110.
- Grosvenor, T. (1988). High axial lenght/corneal radius ratio as a risk factor in the development of myopia. Optom. Vis. Sci., 65, 689-696.
- Grosvenor, T. P. (2004). Optometría de atención primaria (4.a ed.). Boston: Butterworth-Heinemann.
- Hitzenberger, C. K. (1991). Optical measurement of the axial eye length by laser Doppler interferometry. Invest. Ophthalmol. Vis. Sci., 32, 616-624.
- Jaffe, G. J. y Caprioli, J. (2004). Optical coherente tomography to detect and manage retinal disease and glaucoma. Am. J. Ophthalmol., 137, 156-169.
- Kirwan, C., O’Keefe, M. y Lanigan, B. (2006). Corneal hysteresis and intraocular pressure measurement in children using the Reichert Ocular Response Analyzer. Am. J. Ophthalmol., 142, 990-992.
- Kotecha, A. (2007). What biomechanical properties of the cornea are relevant for the clinician? Surv. Ophthalmol., 52, S109-S114.
- Lim, L., Gazzard, G., Chan, Y.-H., Fong, A., Kotecha, A., Sim, E.-L., Tan, D., Tong, L. y Saw, S.-M. (2008a). Cornea biomechanical characteristics and their correlates with refractive error in singaporean children. Invest. Ophthalmol. Vis. Sci., 49, 3852-3857.
- Lim, L., Gazzard, G., Chan, Y. H., Fong, A., Kotecha, A., Sim, E. L., Tan, D., Tong, L. y Saw, S. M. (2008b). Corneal biomechanics, thickness and optic disc morphology in children with optic disc tilt. Br. J. Ophthalmol., 92, 1461-1466.
- Luce, D. A. (2005). Determining in vivo biomechanical properties of the cornea with an ocular response analyzer. J. Cataract. Refract. Surg., 31, 156-162.
- Menezo, J. L. y España, E. (2006). Técnicas exploratorias en oftalmología. Barcelona: Espaxs.
- Mohamed, S., Lee, G. K.., Rao, S. K., Wong, A. L., Cheng, A. C., Li, E. Y., Chi, S. C. y Lam, D. S. (2007). Repeatability and reproducibility of pachymetric mapping with visante anterior segment-optical coherence tomography. Invest. Ophthalmol. Vis. Sci., 48, 5499-5504.
- Mutti, D. O., Frane, S., Lin, W. K., Sholtz, R. I. y Zadnik, K. (1998). Cross-sectional changes in crystalline lens curvature and power in infants. Optom. Vis. Sci., 75, 70.
- Ortiz, D., Piñero, D., Shabayek, M. H., Arnalich-Montiel, F. y Alio, J. L. (2007). Corneal biomechanical properties in normal, post-laser in situ keratomileusis, and keratoconic eyes. J. Cataract. Refract. Surg., 33, 1371-1375.
- Patella, V. M. (2003). Establishment of normative reference values for retinal nerve fiber layer thickness measurements. Dublín: Carl Zeiss Meditec.
- Prata, T. S., Lima, V. C., Guedes, L. M., Biteli, L. G., Teixeira, S. H., Moraes, C. G. de, Ritch, R. y Paranhos, A. Jr. (2012). Association between corneal biomechanical properties and optic nerve head morphology in newly diagnosed glaucoma patients. Clinical and Experimental Ophthalmology, 40, 682-688.
- Shen, M., Fan, F., Xue, A., Wang, J., Zhou, X. y Lu, F. (2008). Biomechanical properties of the cornea in high myopia. Vision Research, 48, 2167-2171.
- Sheng, H., Bottjer, C. A. y Bullimore, M. A. (2004). Ocular component measurement using the Zeiss IOL Master. Optom. Vis. Sci., 81, 27-34.
- Song, Y., Congdon, N., Li, L., Zhou, Z., Choi, K., Lam, D. S., Pang, C. P., Xie, Z., Liu, X., Sharma, A., Chen, W. y Zhang, M. (2008). Corneal hysteresis and axial length among Chinese secondary school children: the Xichang Pediatric Refractive Error Study (X-PRES), report No. 4. Am. J. Ophthalmol., 145, 819-826.
- Stodmeiser, R. (1998). Applanation tonometry and correction according to corneal thickness. Acta Ophthalmol. Scand., 76, 319-24.
- Suzuki, S., Suzuki, Y., Iwase, A. y Araie, M. (2005). Corneal thickness in an ophthalmologically normal Japanese population. Ophthalmology, 112, 1327-1336.
- Tong, L., Saw, S. M., Siak, J. K., Gazzard, G. y Tan, D. (2004). Corneal thickness determination and correlates in Singaporean schoolchildren. Invest. Ophathalmol. Vis. Sci., 45, 4004-4009.
- Viqueira, V., Martínez Verdú, F. M. y Fez, M. D. de (2003). Óptica fisiológica: modelo paraxial y compensación óptica del ojo. Alicante: Universidad de Alicante.
- Visante OCT (2007). User manual: model 1000: Carl Zeiss Meditec. Wang, J., Thomas, J., Cox, I. y Rollins, A. (2004). Noncontact measurements of central corneal epithelial and flap thickness after laser in situ keratomileusis. Invest. Ophthalmol. Vis. Sci., 45, 1812-1816.
- Yebra-Pimantel, E., González-Méijome, J. M., Garcia- Resúa, C. y Giráldez-Fernández, M. J. (2008). Relación entre los componentes ópticos oculares e implicaciones en el proceso de emetropización. Arch. Soc. Esp. Oftalmol., 83, 307-316.
- Yebra-Pimentel, E., Giráldez, M. J., Glez.-Méijome, J. M., Cerviño, A., García-Resúa, C. y Parafita, M. A. (2004). Variación de la ratio longitud axial/radio corneal (LA/RC) con el estado refractivo ocular. Relación con los componentes oculares. Arch. Soc. Esp. Oftalmol., 79, 317-324.
- Zadnik, K., Mutti, D. O., Mitchell, G. L., Jones, L. A., Burr, D. y Moeschberger, M. L. (2004). Normal eye growth in emmetropic schoolchildren. Optom.Vis. Sci., 81, 819-828.
- Zhang, H., Xu .L, Chen, C. y Jonas, J. B. (2008). Central corneal thickness in adult Chinese: association with ocular and general parameters. The Beijing Eye Study. Graefes. Arch. Clin. Exp. Ophthalmol., 246, 587-92.
- Zhao, P. S., Wong, T. Y., Wong, W.-L., Saw, S.-M. y Aung, T. (2007). Comparison of central corneal thickness measurements by visante anterior segment optical coherence tomography with ultrasound pachymetry. Am. J. Ophthalmol., 143, 1047-1049.