Análisis cuantitativo salival en pacientes con liquen plano oralestudio en 100 casos

Abstract

Objective: A study is made to determine whether patients with oral lichen planus (OLP) present alterations in whole saliva flow, and to establish the relation between such alterations and the different clinical forms of OLP. Material and methods: A quantitative study was made of whole salivary flow at rest (WSR) and following stimulation (WSS) with 10% citric acid in 100 patients with OLP and 42 healthy controls. The results obtained were expressed in milliliters after 5 min. Among the patients with OLP, these values were in turn related to the clinical presentations of the lesions. Results: The mean WSR in the OLP group (1.35 ml/5 min., standard deviation (SD) = 0.87) was very similar to that observed among the controls (1.33 ml/5 min., SD = 0.76)(p = 0.86). Similarly, no significant differences were recorded between the two groups in terms of WSS (6.45 ml/5 min., SD = 2.64 and 6.51 ml/5 min., SD = 3.93)(p = 0.91). The comparative statistical analysis revealed no differences between the white and atrophic-erosive forms in terms of either WSR (p = 0.59) or WSS (p = 0.39). Similarly, the extent of the oral lesions was unrelated to WSR (p = 0.37) and WSS (p = 0.15). Conclusions: No significant association was established between OLP and altered whole salivary flow at rest and upon stimulation, and no relationship was observed between whole saliva production among the patients and the different clinical types of OLP.