Prevalence of salivary Epstein-Barr virus in potentially malignant oral disorders and oral squamous cell carcinoma

  1. Leticia Bagán Debón
  2. Dolores Ocete Mochón
  3. Manuel Leopoldo Rodado
  4. Judith Murillo Cortés
  5. José María Díaz Fernández
  6. Rafael Medina-Gonzalez
  7. Concepción Gimeno Cardona
  8. José Vicente Bagán Sebastián
Revista:
Medicina oral, patología oral y cirugía bucal. Ed. inglesa

ISSN: 1698-6946

Ano de publicación: 2016

Volume: 21

Número: 2

Páxinas: 5

Tipo: Artigo

DOI: 10.4317/MEDORAL.20785 DIALNET GOOGLE SCHOLAR lock_openAcceso aberto editor

Outras publicacións en: Medicina oral, patología oral y cirugía bucal. Ed. inglesa

Resumo

Background: To analyze the presence of salivary Epstein-Barr virus (EBV) DNA in oral squamous cell carcinoma and potentially malignant oral disorders. Material and Methods: Three groups were studied: Group 1 (12 oral squamous cell carcinomas (OSCC)), Group 2 (12 potentially malignant oral disorders (PMD)) and Group 3 (47 healthy controls). EBV DNA salivary analysis was performed by PCR. Results: The highest percentage of positive salivary EBV DNA corresponded to the OSCC group (58.3%), followed by the PMD group (41.7%) and the controls (40.4%). The differences between groups were not statistically significant, however (p>0.05). Conclusions: Salivary EBV DNA was more prevalent in OSCC than in PMD or the controls.

Fonte de datos: Dialnet