Ayahuascafarmacología, efectos agudos, potencial terapéutico y rituales

  1. Aliño, Marta
  2. Gadea Doménech, Marien
  3. Pérez San Miguel, Joana
  4. Espert Tortajada, Raúl
Revista:
Revista española de drogodependencias

ISSN: 0213-7615

Ano de publicación: 2015

Número: 1

Páxinas: 75-91

Tipo: Artigo

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Outras publicacións en: Revista española de drogodependencias

Resumo

Ayahuasca is a botanical hallucinogenic preparation which is made up of Banisteriopsis caapi and Psychotria viridis, consumed by indigenous groups of the Amazonia region. This beverage contains the serotoninergic agonist N,N-dimethyltryptamine (DMT) and monoamine oxidase-inhibiting alkaloids (harmine, harmaline and tetrahydroharmine). Scientific literature has until now suggested that the administration or acute consumption of ayahuasca is not badly tolerated, even in situations where consumers have endured chronic use of the substance, no study having detected any effect of toxicological nature in humans. However, taking into account the limitations of performing most studies on a young and healthy sample, and the scant data on preexisting hepatic and cardiac pathologies, as well as the combined use of ayahuasca with other substances, a warning about the contraindication of ayahuasca use is suggested. The aim of this work is to put forward an overview through the composition and action mechanisms of ayahuasca and the desired and adverse effects of its administration. The use of this preparation as a new pharmacological therapy on substance abuse and affective disorders is explained, as well as a brief description regarding the connotations of ayahuasca use in organized rituals.

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Fonte de datos: Dialnet