Úlcera eosinofílica lingualun reto diagnóstico de patogénesis controvertida
- Beatriz Vera Sirera
- J. Delhom
- Carmen Baquero Ruíz de la Hermosa
- Francisco José Vera Sempere
ISSN: 1130-0558, 2173-9161
Año de publicación: 2013
Volumen: 35
Número: 3
Páginas: 128-132
Tipo: Artículo
Otras publicaciones en: Revista española de cirugía oral y maxilofacial: Publicación Oficial de la Sociedad Española de Cirugía Oral y Maxilofacial
Resumen
Eosinophilic ulcer, also know as traumatic ulcerative granuloma with stromal eosinophilia, is a rare and benign ulcerative lesion of oral mucosa that has a persistent progression, often requiring a differential clinical diagnosis. The diagnosis is only established from histopathological studies, which frequently show morphological features that may be suggestive of a lymphoproliferative process, resulting in a controversial pathogenesis that is still not clarified today. We report the clinical and pathological observations of an eosinophilic ulcer affecting a woman 76 year-old woman. A biopsy was performed twice on a 2.5 cm diameter ulcer affecting the lingual edge. After a clinical follow-up of 5 months, a self-limiting course with the production of a scar was verified. She has currently been scheduled for an extended 24-month clinical follow-up. The morphological and immunohistochemical features found in the biopsy study are presented, and the pathogenesis hypothesis of this uncommon ulcerative lesion is discussed.