Eficacia de las intervenciones farmacológicas en el tratamiento de la hiperactividad

  1. Mulas, F.
  2. Pastor Soriano, Juan Carlos
  3. Roselló Miranda, Belén
  4. Miranda Casas, Ana
Revista:
Psicothema

ISSN: 0214-9915

Ano de publicación: 1996

Volume: 8

Número: 1

Páxinas: 89-105

Tipo: Artigo

DIALNET GOOGLE SCHOLAR lock_openAcceso aberto editor

Outras publicacións en: Psicothema

Resumo

El presente estudio trata de sintetizar, integrar y discutir los principales resultados constatados en la investigación con respecto a la eficacia de las intervenciones farmacológicas más frecuentemente utilizadas en el tratamiento de la hiperactividad. Este trabajo constituye la primera parte de un estudio más amplio basado en una selectiva revisión y análisis cualitativo de la literatura publicada sobre este tópico en los últimos siete años. Junto a la metodología empleada se ofrece una descripción general de los estudios incluidos en el análisis, así como de las muestras utilizadas. Las conclusiones relativas a los tratamientos psicológicos y combinados (psicológicos y farmacológicos) quedan recogidas en un trabajo complementario.

Referencias bibliográficas

  • Alessandri, S.M. y Schramm, K. (1991). Effects of dextroanphetamine on the cognitive and social play of a preschooler with ADHD. Journal of the American Academy of Adolescent Psychiatry, 30, 768-773.
  • Aman, M.G., Mitchel, E.A. y Turbott, S. (1987). The effects of essential fatty acid supplementation by efamol in hyperactive children. Journal of Abnormal Child Psychology, 15, 79-90.
  • Aman, M.G. y Turbott, S.H. (1991). Prediction of clinical response in children taking methylphenidate. Journal of Autism and Developmental Disorders, 21, 211- 227.
  • Anastopoulus, A.D., Dupaul, G.J. y Barkley, R.A. (1991). Stimulant medication and parent training therapies for attention deficit hiperactivity disorder. Journal of Learning Disabilities, 24, 210-218.
  • Arnold, L.E., Kleykamp, D, Votolato, N.A., Taylor, W.A., Kontras, S.B. y Tobin, K. (1989). Gamma-linolenic acid for attention- deficit hyperactivity disorder: placebo-controlled comparison to D-amphetamine. Biological Psychiatry, 25, 222-228.
  • Arnold, L.E., Votolato, N.A., Kleykamp, D., Baker, G.B. y Bornstein, R. (1990). Does hair zinc predict amphetamine improvement of ADD/Hiperactivity? International Journal of Neuroscience, 50, 103-107.
  • Barkley, R.A. (1977). A review of stimulant drug research with hyperactivity children. Journal of Child Psychology and Psiquiatry, 18, 137-165.
  • Barkley, R.A. (1988). The effects of methylphenidate on the interactions of preschool ADHD children with their mothers. Journal of the American Academy of Child and Adolescent Psychiatry, 27, 336-341.
  • Barkley, R.A. (1989). The problem of stimulies control and rule-governed behavior in attention-deficit disorder with hiperactivity. En L.M. Bloomingdale y J. Swanson (eds.). Attention deficit disorder. New York: Pergamon Press.
  • Barkley, R.A. (1991). Attention-deficit hiperactivity disorder. A clinical workbook. New York: Guilford-Press.
  • Barkley, R.A., Fischer, M., Newby, R.Y., Breen, M. (1988). Development of multi-method clinical protocol for assessing stimulant drug responses in ADHD children. Journal of Clinical Child Psychology, 17, 14-24.
  • Barrickman, L., Noyes, R., Kuperman, S., Schumacher, E. y Verda, M. (1991). Treatment of ADHD with fluoxetine: a preliminary trial. Journal of the American Academy of Child and Adolescent Psychiatry, 30, 762- 767.
  • Biederman, Y., Baldessarini, R., Wright, V., Knee, D. y Harmatz, J. (1989a). A doubleblind placebo controlled study of desipramine in the treatment of ADD: I Efficacy. Journal of the American Academy of Child and Adolescent Psychiatry, 28, 777-784.
  • Biederman, Y., Baldessarini, R., Wright, V., Knee, D., Harmatz, J.S. y Goldblatt, A. (1989b). A double-blind placebo controlled study of desipramine in the treatment of ADD: II Serum drug levels and cardiovascular findings. Journal of the American Academy of Child and Adolescent Psychiatry, 28, 903-911.
  • Brown, R.T. y Sexson, S.B. (1988). A controled trial of methyphenidate in black adolescentes. Clinical Pediatrics, 27, 74-81.
  • Carlson, C.L., Pelham, W.E., Swanson, J.M. y Wagner, J.L. (1991). A divided analysis of the arithmetic performance of children with attention deficit hyperactivity disorder. Journal of Child Psychology and Psychiatry, 32, 463-471.
  • Donnelly, M., Rapoport, J.L., Potter, W., Oliver J, Keysor, C.S, y Murphy, D.L. (1989). Fenfluramine and dextroamphetamine treatment of childhood hyperactivity. Archives of General Psychiatry, 46, 295-212.
  • Eisenberg, J., Asnis, G.M., Vanpraag, H.M. y Vela, R.M. (1988). Effect of tyrosine on attention deficit disorder with hyperactivity. Journal of Clinical Psychiatry, 49, 193- 195.
  • Elia, J., Borchending, B.G., Rapoport, J.L. y Keysor, C.S. (1990). Methylphenidate and dextroamphetamine treatments of hyperactivity: are there true nonresponders? Psychiatry Research, 35, 141-155.
  • Evans, R.W., Gualteri, C.T. y Hicks, R.E. (1986). A neuropathic substrate for stimulant drug effects in hyperactivity children. Clinical Neuropharmacology, 9, 264-281.
  • Evans, S.W. y Pelham, W.E. (1991). Psychostimulant effects on academic and behavioral measures for ADHD junior high school students in lecture fermet classroom. Journal of Abnormal Child Psychology, 19, 537- 552.
  • Gadow, K.D. (1988). Attention deficit disorder and hyperactivity: pharmacotherapies. En J.L. Matson (ed.). Handbook of treatment approaches in childhood psychopatology. New York: Plenum Press.
  • Haenlein, M. y Caul, W.F. (1987). Attention deficit disorder with hyperactivity: a specific hypothesis of reward disfunction. Journal of the American Academy of Child and Adolescent Psychiatry, 26, 356-362.
  • Halliday, R., Callaway, E., y Rosenthal, R. (1984). The visual ERP predicts clinical response to methylphenidate in hyperactive children. Psychophisiology, 21, 114-121.
  • Hinshaw, S.P., Heller, T. y McHale, J.P. (1992). Covert antisocial behavior in boys with attention-deficit hyperactivity disorder: external validation and effects of methylphenidate. Journal of Consulting and Clinical Psychology, 60, 274-281.
  • Hinshaw, S.P., Henker, B., Whalen, C.K., Erhard, D. y Duunington, R. (1989). Aggressive, prosocial and nonsocial behavior in hyperactivity boys: dore effects of methylphenidate in naturalistic settings. Journal of Consulting and Clinical Psychology, 57, 636-643.
  • Kaplan, S.L., Busner, J., Kupietz, S., Wasserman, E. y Segal, B. (1990). Effects of methylphenidate on adolescents with aggressive conduct disorder and ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 719-723.
  • Keith, R.W. y Engineer, P. (1991). Effects of methylphenidate on the auditory processing abilities of children with attention-deficit hyperactivity disorder. Journal of Learning Disabilities, 24, 631-636.
  • Klorman, R., Brumaghim, J.T., Fizpatrick, P. y Borgstedt, A.D. (1990). Clinical effects of a controled trial of methylphenidate on adolescents with attention deficit disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 702-709.
  • Klorman, R., Brumaghim, J.T., Fizpatrick, P. y Borgstedt, A.D. (1992). Methylphenidate reduces abnormalities of stimules classification in adolescents with attention deficit disorder. Journal of Abnormal Psychology, 101, 130-138.
  • Klorman, R., Brumaghim, J.T., Salzman, L.F., Strauss, A.D., McBride, M. y Loeb, S. (1990). Effects of methylphenidate on processing negativities in patients with attention-deficit hyperactivity disorder. Psychophysiology, 27, 238-337.
  • Klorman, R., Coons, H.W. y Borgstedt, A.D. (1987). Effects of methylphenidate on adolescents with a childhood history of attention deficit disorder. I Clinical findings. Journal of the American Academy of Child and Adolescent Psychiatry, 26, 363-367.
  • Kupietz, S.S., Winsberg, B.G., Richardson, E., Maitinsky, S. y Mendell, N. (1988). Effects of methylphenidate dosage in hyperactive reading-disabled children: I Behavior and cognitive performance effects. Journal of the American Academy of Child and Adolescent Psychiatry, 27, 70-77.
  • Kutcher, S.P. (1986). Assesing and treating attention deficit disorder in adolescents. British Journal of Psychiatry, 149, 710-715.
  • Lambert, N. y Sandoval, J. (1980). The prevalence of learning disabilities in a sample of children considered hyperactive. Journal of Abnormal Child Psychology, 8, 33-50.
  • Levinson, H.N. (1991). Dramatic favorable responses of children with learning disabilities or dyslexia and attention deficit disorder to antimotion sickners medications: four cases reports Perceptual and Motor Skills, 73, 723-738.
  • Levy, F. y Hobbes, G. (1988). The action of stimulant medication in attention deficit disorder with hyperactivity: dopaminergic, noradrenergic, or both? Journal of the American Academy of Child and Adolescent Psychiatry, 27, 802-805.
  • Millich, R., Licht, B.G., Murphy, D. y Pelham, W.E. (1989). Attention-deficit hyperactivity disordered boy´s evaluations of and attributions for task performance on medication versus placebo. Journal of Abnormal Psychology, 98, 280-284.
  • Pelham, W.E., Murphy, D.A., Vannatta, K., Milich, R., Licht, B.G., Gnagy, E.M., Greenslade, K.E., Kreiner, A. y Vodde-Hamilton, M. (1992). Methylphenidate and attributions in boys with attention-deficit hyperactivity disorder. Journal of Consulting and Clinical Psychology, 60, 282-292.
  • Pelham, W.E., Vodde-Hamilton, M., Murphy, D., Greenstein, J. y Vallano, G. (1991). The effects of methylphenidate on ADHD adolescents in recreational, peer group and classroom settings. Journal of Clinical Child Psychology, 20, 293-300.
  • Pelham, W.E., Walter, J.L., Sturges, J.Y. y Hoza, J. (1989). Comparative effects of methylphenidate on ADD girls and ADD boys. Journal of the American Academy of Child and Adolescent Psychiatry, 28, 773- 776.
  • Physician´s Desk Refence (1989). Medical Economics Company. New York: Oradell.
  • Rapport, M.D., DuPaul, G.J. y Kelly, K.L. (1989). Attention-deficit hyperactivity disorder.and methylphenidate: the relationship between gross body weight and drug response in children. Psychopharmacology Bulletin, 25, 285-290.
  • Richardson, E., Kupietz, S.S., Winsberg, B.G., Maitinsky, S. y Mendell, N. (1988). Effects of methylphenidate dosage in hyperactive reading-disabled children: II. Reading achievement. Journal of the American Academy of Child and Adolescent Psychiatry, 27, 78-87.
  • Riddley, M.A., Hardin, M.T., Cho, S.CH., Woolston, J.L. y Leckman, J. (1988). Desipramine treatment of boys with attention-deficit hyperactivity disorder.and tics: preliminary clinical experience. Journal of the American Academy of Child and Adolescent Psychiatry, 27, 811-814.
  • Ross, D.M. y Ross, S.A. (1982). Hyperactivity: current issues, research and theory. New York: Wiley.
  • Safer, D.J. y Krager, J.M. (1988). A survey of medication treatment hyperactive/inattentive students. Journal of American Medical Association, 260, 2256-2258.
  • Simeon, J.G., Ferguson, H.B. y Van Wick Fleet, J. (1986). Bupropion effects in attention deficit and conduct disorders. Canadian Journal of Psychiatry, 31, 581-585.
  • Speltz, M.L., Varley, C.K., Peterson, K. y Beilke, R.L. (1988). Effects of dextroamphetamine and contingency manegement on a preeschooler with ADHD and oppositional defiant disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 27, 175-178.
  • Sverd, J., Gadow, K.D. y Paolicelly, L.M. (1989). Methylphenidate treatment of attention-deficit hyperactivity disorder in boys with Tourette´s syndrome. Journal of the American Academy of Child and Adolescent Psychiatry, 28, 574-579.
  • Swanson, J.M., Sandman, C.A., Deutsch, C. y Baren, M. (1983). Methylphenidate (ritalin) given with or before breakfast. I. Behavioral, cognitive and electrophysiological effects. Pediatry, 72, 49-55.
  • Tannock, R. y Schachar, R. (1992). Methylphenidate and cognitive perseveration in hyperactive children. Journal of Child Psychology and Psychiatry, 33, 1217-1228.
  • Trott, G.E., Friese, H.J., Menzel, M. y Nissen, G. (1992). Use of moclobemide in children with attention deficit hyperactivity disorder. Psychopharmacology, 106, 134-136.
  • Wender, P.H. y Reimherr, F.W. (1990). Bupropion treatment of attention-deficit hyperactivity disorder in adults. American Journal of Psychiatry, 147, 1018-1020.
  • Wilens, T.H., Steingard, R. y Biederman, J. (1992). Clomipramine for comorbid conditions. Journal of the American Academy of Child and Adolescent Psychiatry, 31, 171.
  • Zametkin, A.J., Karoum, F. y Rapoport, J.L. (1987). Treatment of hyperactivity children with D-phenylalanine. American Journal of Psychiatry, 144, 792-794.
  • Zametkin, A.J., Reeves, J.C., Webster, L. y Werry, J.S. (1986). Promethazine treatment of children with attention deficit disorder with hyperactivity. Ineffective and unpleasant. Journal of the American Academy of Child Psychiatry, 25, 854-856.
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