Molecular mechanisms of cytoplasmic polyadenylation in drosophila

  1. Villaba Izquierdo, Ana
Supervised by:
  1. Fátima Gebauer Hernández Director

Defence university: Universitat de València

Fecha de defensa: 09 November 2012

Committee:
  1. Raúl Méndez de la Iglesia Chair
  2. Nuria Paricio Secretary
  3. Elmar Wahle Committee member

Type: Thesis

Teseo: 333196 DIALNET lock_openRODERIC editor

Abstract

Drosophila early embryogenesis is an ideal system to study control of gene expression at the post transcriptional level, since at this stage there is little or no transcription. This first section gives a brief overview on early development in Drosophila. Since in this thesis, toll, a maternal mRNA implicated in the establishment of the dorso-ventral axis during early stages of embryonic development, is used as a model to uncover the molecular mechanism of cytoplasmic polyadenylation at this developmental stage.