UFDI
Digestive and Inflammatory Diseases Research Unit
Publications (50) Publications in which a researcher has participated
2025
2024
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Oligodendroglial fatty acid metabolism as a central nervous system energy reserve
Nature Neuroscience, Vol. 27, Núm. 10, pp. 1934-1944
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TFEB controls syncytiotrophoblast formation and hormone production in placenta
Cell Death and Differentiation, Vol. 31, Núm. 11, pp. 1439-1451
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USF2 and TFEB compete in regulating lysosomal and autophagy genes
Nature communications, Vol. 15, Núm. 1, pp. 8334
2023
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Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation
Nature communications, Vol. 14, Núm. 1, pp. 3911
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Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex
Nature, Vol. 614, Núm. 7948, pp. 572-579
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TFEB-mediated lysosomal exocytosis alleviates high-fat diet-induced lipotoxicity in the kidney
JCI Insight, Vol. 8, Núm. 4
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The lysosomal Ragulator complex activates NLRP3 inflammasome in vivo via HDAC6
EMBO Journal, Vol. 42, Núm. 1
2022
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Disrupting the MYC-TFEB Circuit Impairs Amino Acid Homeostasis and Provokes Metabolic Anergy
Cancer Research, Vol. 82, Núm. 7, pp. 1234-1250
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Non-canonical mTORC1 signaling at the lysosome
Trends in Cell Biology, Vol. 32, Núm. 11, pp. 920-931
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The lysosomal system: Physiology
Lysosomal Storage Disorders: A Practical Guide (wiley), pp. 9-18
2021
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A gene toolbox for monitoring autophagy transcription
Cell Death and Disease, Vol. 12, Núm. 11
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GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis
Science Advances, Vol. 7, Núm. 40
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TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
Molecular Metabolism, Vol. 47
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TFEB links MYC signaling to epigenetic control of myeloid differentiation and acute myeloid leukemia
Blood cancer discovery, Vol. 2, Núm. 2, pp. 162-185
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TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading
Molecular Psychiatry, Vol. 26, Núm. 10, pp. 5925-5939
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The neutrophil secretome as a crucial link between inflammation and thrombosis
International Journal of Molecular Sciences, Vol. 22, Núm. 8
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The rapidly evolving view of lysosomal storage diseases
EMBO Molecular Medicine, Vol. 13, Núm. 2
2020
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GADD34 is a modulator of autophagy during starvation
Science Advances, Vol. 6, Núm. 39
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LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury
Nature Cell Biology, Vol. 22, Núm. 10, pp. 1252-1263